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用于恶性大肠梗阻的金属支架

Metal stents for malignant colorectal obstruction.

作者信息

Repici Alessandro, Pagano Nico, Hervoso Cristina Marfinati, Danese Silvio, Nicita Rinaldo, Preatoni Paoletta, Malesci Alberto

机构信息

Department of Gastroenterology, Digestive Endoscopy Unit, IRCCS Istituto Clinico Humanitas, Via Manzoni 56, I-20089 Rozzano, Milan, Italy.

出版信息

Minim Invasive Ther Allied Technol. 2006;15(6):331-8. doi: 10.1080/13645700601037954.

Abstract

Malignant obstruction of the colon occurs in 7-25% of patients with colorectal cancer. As emergency laparotomy is reported to have relatively high morbidity and mortality rate, there is a need for alternative procedures with reduced complication rates. Over the last decade colorectal stenting has been reported as an alternative endoscopic method to relieve acute colonic obstruction. With the availability of more sophisticated stents and stent delivery systems, this approach has been used as a palliative method and as a pre-operative bridge to facilitate one-stage surgical resection of primary colonic tumors. Technical and clinical successes have been reported in 80-100% of treated patients. Distal lesions are more common and theoretically easier to stent although lesions within the ascending colon have been successfully managed. Minor complications include transient anorectal pain, tenesmus and rectal bleeding. However, stent migration and colonic perforation are also well recognized. Despite the fact that no randomized controlled studies have yet been performed, literature data show that colonic stenting is a safe and effective procedure and can reduce costs, avoiding the need for colostomy and improving the quality of life of patients with advanced disease.

摘要

7%至25%的结直肠癌患者会出现结肠恶性梗阻。由于据报道急诊剖腹手术的发病率和死亡率相对较高,因此需要采用并发症发生率较低的替代手术。在过去十年中,结肠支架置入术已被报道为一种缓解急性结肠梗阻的内镜替代方法。随着更先进的支架和支架输送系统的出现,这种方法已被用作姑息治疗方法和术前桥梁,以促进原发性结肠肿瘤的一期手术切除。据报道,80%至100%的接受治疗的患者在技术和临床方面取得了成功。远端病变更为常见,理论上更容易置入支架,尽管升结肠内的病变也已成功处理。轻微并发症包括短暂的肛门直肠疼痛、里急后重和直肠出血。然而,支架移位和结肠穿孔也很常见。尽管尚未进行随机对照研究,但文献数据表明,结肠支架置入术是一种安全有效的手术,可降低成本,避免结肠造口术的需要,并改善晚期疾病患者的生活质量。

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