Trishkina E V, Kanaev S V, Gafmon G I, Il'in N V
Vopr Onkol. 2006;52(3):361-6.
Clinical efficacy of combined treatment of 383 patients who had undergone conservative surgery for extremity soft-tissue sarcomas (combined treatment -188; surgery alone - 195, control) was assessed. The comparison, which included prognostic factors, established the advantages of combined treatment in all groups. Thus, overall 5-year survival time was in 64.3+/-2.8%, with combined treatment - 72.2+/-3.3% and surgery - 56.8+/-3.5%, t>2. Application of radiotherapy as a component of combined modality treatment made feasible a wider range of organ-saving operations. Differences in the frequency of postoperative complications after surgery and combined treatment were insignificant and of similar patterns.