血液及血液制品高危接受者中抗丙型肝炎病毒、乙肝表面抗原及艾滋病毒抗体的流行情况。

Prevalence of anti HCV, HBsAg and HIV antibodies in high risk recipients of blood and blood products.

作者信息

Chakrabarti S, Pradhan P, Roy A, Hira M, Bandyopadhyay G, Bhattacharya D K

机构信息

Dept. of Pathology, NRS Medical College.

出版信息

Indian J Public Health. 2006 Jan-Mar;50(1):43-4.

PMID:17193761

Abstract

Along with hepatitis B virus (HBV) and human immunodeficiency virus (HIV), Hepatitis C virus (HCV) is emerging as a major transfusion hazard. 22 cases of haemophilia (A 19, B 3) and 20 cases of thalassaemia (2 16, E(2) 4) constituted the study group. Patients tested for anti HCV (using third generation ELISA), HBsAg and antibodies to HIV I and II. Prevalence of anti HCV was 54.5% in haemophilics and 5% in thalassaemics. HBsAg was detected in 9.09% haemophilics and 5% thalassaemics. No anti HIV was detected in this cohort. Anti HCV seropositivity in haemophilics has increased compare to previous studies.

摘要

与乙型肝炎病毒（HBV）和人类免疫缺陷病毒（HIV）一样，丙型肝炎病毒（HCV）正成为主要的输血危害。19例甲型血友病、3例乙型血友病患者以及20例地中海贫血患者（其中16例为β型，4例为E型）构成了研究组。对患者进行了抗HCV检测（采用第三代酶联免疫吸附测定法）、HBsAg检测以及HIV I和II抗体检测。血友病患者中抗HCV的患病率为54.5%，地中海贫血患者中为5%。在血友病患者中检测到HBsAg的比例为9.09%，在地中海贫血患者中为5%。该队列中未检测到抗HIV。与之前的研究相比，血友病患者中抗HCV血清阳性率有所上升。