Ebe K, Funazaki T, Aizawa Y, Shibata A, Fukuda T
First Department of Internal Medicine, Niigata University School of Medicine, Japan.
Pacing Clin Electrophysiol. 1991 Aug;14(8):1222-7. doi: 10.1111/j.1540-8159.1991.tb02859.x.
Polyurethane pacemaker leads are widely used nowadays. However, only a few studies have been done to investigate the fixation mechanism of polyurethane leads. To elucidate how pacemaker leads are fixed at the early phase after implantation, polyurethane-insulated tined ventricular leads were implanted in seven mongrel dogs. One to 4 months later, tips of the leads were anchored among the trabeculae and the distal part of the leads were encapsulated by whitish fibrous tissue. It was found that not organized thrombi, but cell reaction with various stages of inflammatory cells was responsible for forming the fibrous tissue. We attempted to remove the lead by delivering radiofrequency wave through the lead. However, no lead could be removed.