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非惊厥性癫痫持续状态的精神症状

Psychiatric manifestations of nonconvulsive status epilepticus.

作者信息

Riggio Silvana

机构信息

Department of Psychiatry, Mount Sinai Medical Center, New York, NY 10029, USA.

出版信息

Mt Sinai J Med. 2006 Nov;73(7):960-6.

Abstract

Nonconvulsive status epilepticus (NCSE) is clinically characterized by altered mental status and the diagnosis is confirmed by electroencephalography. Absence status (AS) and complex partial status (CPS) are the two primary types of NCSE. Patients in NCSE may exhibit a wide range of clinical presentations including subtle memory deficits, bizarre behavior, psychosis, or coma. While prognosis is dependent on the underlying etiology and possibly related to duration of the event, there is limited research in this area. Treatment focuses on correcting underlying pathologic abnormalities such as hyponatremia or drug toxicity, and initiating pharmacologic therapy. The benzodiazepines are considered the first line treatment for both AS and CPS.

摘要

非惊厥性癫痫持续状态(NCSE)的临床特征为精神状态改变,其诊断通过脑电图得以证实。失神状态(AS)和复杂部分性状态(CPS)是NCSE的两种主要类型。NCSE患者可能表现出广泛的临床症状,包括细微的记忆缺陷、怪异行为、精神病或昏迷。虽然预后取决于潜在病因,可能还与发作持续时间有关,但该领域的研究有限。治疗重点在于纠正潜在的病理异常,如低钠血症或药物毒性,并启动药物治疗。苯二氮䓬类药物被认为是AS和CPS的一线治疗药物。

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