Des Jarlais Don C, Arasteh Kamyar, Perlis Theresa, Hagan Holly, Abdul-Quader Abu, Heckathorn Douglas D, McKnight Courtney, Bramson Heidi, Nemeth Chris, Torian Lucia V, Friedman Samuel R
Beth Israel Medical Center, New York, New York 10038, USA.
AIDS. 2007 Jan 11;21(2):231-5. doi: 10.1097/QAD.0b013e3280114a15.
To compare HIV prevalence among injecting and non-injecting heroin and cocaine users in New York City. As HIV is efficiently transmitted through the sharing of drug-injecting equipment, HIV infection has historically been higher among injecting drug users.
Two separate cross-sectional surveys, both with HIV counseling and testing and drug use and HIV risk behavior questionnaires.
Injecting and non-injecting heroin and cocaine users recruited at detoxification and methadone maintenance treatment from 2001-2004 (n = 2121) and recruited through respondent-driven sampling from a research storefront in 2004 (n = 448).
In both studies, HIV prevalence was nearly identical among current injectors (injected in the last 6 months) and heroin and cocaine users who had never injected: 13% [95% confidence interval (CI), 12-15%] among current injectors and 12% (95% CI, 9-16%) among never-injectors in the drug treatment program study, and 15% (95% CI, 11-19%) among current injectors and 17% (95% CI, 12-21%) among never injectors in the respondent driven sampling storefront study. The 95% CIs overlapped in all gender and race/ethnicity subgroup comparisons of HIV prevalence in both studies.
The very large HIV epidemic among drug users in New York City appears to be entering a new phase, in which sexual transmission is of increasing importance. Additional prevention programs are needed to address this transition.
比较纽约市注射海洛因和可卡因者与非注射海洛因和可卡因者中的艾滋病毒感染率。由于艾滋病毒可通过共用注射吸毒器具高效传播,历史上注射吸毒者中的艾滋病毒感染率一直较高。
两项独立的横断面调查,均包含艾滋病毒咨询与检测以及吸毒和艾滋病毒风险行为问卷。
2001年至2004年在戒毒所和美沙酮维持治疗项目中招募的注射及非注射海洛因和可卡因使用者(n = 2121),以及2004年通过应答者驱动抽样从一个研究店面招募的使用者(n = 448)。
在两项研究中,当前注射者(过去6个月内有注射行为)与从未注射过的海洛因和可卡因使用者的艾滋病毒感染率几乎相同:在戒毒治疗项目研究中,当前注射者的感染率为13%[95%置信区间(CI),12 - 15%],从未注射者为12%(95% CI,9 - 16%);在应答者驱动抽样店面研究中,当前注射者为15%(95% CI,11 - 19%),从未注射者为17%(95% CI,12 - 21%)。在两项研究中,艾滋病毒感染率的所有性别和种族/族裔亚组比较中,95%置信区间均有重叠。
纽约市吸毒者中规模极大的艾滋病毒流行似乎正在进入一个新阶段,其中性传播的重要性日益增加。需要更多的预防项目来应对这一转变。