Schachter Steven C
Harvard Medical School, Boston, Massachusetts 02215, USA.
Neurotherapeutics. 2007 Jan;4(1):4-11. doi: 10.1016/j.nurt.2006.11.005.
Many new antiepileptic drugs (AEDs) have become available over the past 15 years. At the same time, the emphasis on treating patients with epilepsy has grown from stopping seizures to avoiding side effects and maximizing quality of life. This review summarizes currently available AEDs, and presents general treatment principles and guidelines for AED selection. Unfortunately, despite the increased treatment options of today, seizure freedom without side effects remains unattainable for too many patients with epilepsy. Consequently, there remains a significant need for further development of new therapies.
在过去15年里，许多新型抗癫痫药物（AEDs）已可供使用。与此同时，对癫痫患者的治疗重点已从控制癫痫发作转向避免副作用并最大限度地提高生活质量。本综述总结了目前可用的AEDs，并提出了AED选择的一般治疗原则和指南。不幸的是，尽管如今治疗选择有所增加，但对太多癫痫患者来说，无副作用地控制癫痫发作仍然无法实现。因此，仍迫切需要进一步开发新的治疗方法。
