采用简短认知行为疗法治疗急性创伤后应激障碍:一项随机对照试验。

Treatment of acute posttraumatic stress disorder with brief cognitive behavioral therapy: a randomized controlled trial.

作者信息

Sijbrandij Marit, Olff Miranda, Reitsma Johannes B, Carlier Ingrid V E, de Vries Mirjam H, Gersons Berthold P R

机构信息

Academic Medical Center of the University of Amsterdam, Department of Psychiatry, Center for Psychological Trauma, Tafelbergweg 25, 1105 BC, Amsterdam.

出版信息

Am J Psychiatry. 2007 Jan;164(1):82-90. doi: 10.1176/ajp.2007.164.1.82.

Abstract

OBJECTIVE

The purpose of this study was to evaluate the efficacy of brief cognitive behavioral therapy for patients with acute posttraumatic stress disorder (PTSD) resulting from various types of psychological trauma.

METHOD

The authors randomly assigned 143 patients with acute PTSD (irrespective of the time criterion), within 3 months after experiencing a traumatic incident, to either brief cognitive behavioral therapy (N=79) or a waiting list comparison group (N=64). Cognitive behavioral therapy consisted of four weekly sessions containing education, relaxation exercises, imaginal exposure, in vivo exposure, and cognitive restructuring. Main outcome measure was PTSD score measured by structured interview; secondary outcomes were anxiety and depression measured by questionnaire. Assessments took place before the intervention and 1 week and 4 months after the intervention.

RESULTS

Symptoms of PTSD, anxiety, and depression decreased in both groups over time. One week after the intervention, the cognitive behavioral therapy group had significantly fewer symptoms of PTSD than the comparison group, but this difference was smaller and no longer significant 4 months after the intervention. Similar results were found for anxiety and depression scores. Subgroup analyses showed that cognitive behavioral therapy led to significantly lower PTSD scores at 4 months in patients with baseline comorbid major depression and in patients who were included within the first month after the traumatic incident both at 1 week and at 4 months.

CONCLUSIONS

Brief early cognitive behavioral therapy accelerated recovery from symptoms of acute PTSD but did not influence long-term results. Brief early cognitive behavioral therapy showed enhanced efficacy in patients with baseline comorbid depression and patients who were included within 1 month after their traumatic experience.

摘要

目的

本研究旨在评估简短认知行为疗法对因各种类型心理创伤导致的急性创伤后应激障碍(PTSD)患者的疗效。

方法

作者将143例急性PTSD患者(不考虑时间标准),在经历创伤事件后的3个月内,随机分为简短认知行为疗法组(N = 79)或等待名单对照组(N = 64)。认知行为疗法包括四周的课程,内容有教育、放松练习、想象暴露、现场暴露和认知重构。主要结局指标是通过结构化访谈测量的PTSD评分;次要结局是通过问卷调查测量的焦虑和抑郁。在干预前、干预后1周和4个月进行评估。

结果

随着时间的推移,两组的PTSD、焦虑和抑郁症状均有所减轻。干预后1周,认知行为疗法组的PTSD症状明显少于对照组,但这种差异在干预后4个月时变小且不再显著。焦虑和抑郁评分也有类似结果。亚组分析表明,对于基线合并重度抑郁症的患者以及在创伤事件后第一个月内纳入的患者,认知行为疗法在4个月时导致PTSD评分显著降低,在1周和4个月时均如此。

结论

早期简短认知行为疗法加速了急性PTSD症状的恢复,但不影响长期结果。早期简短认知行为疗法在基线合并抑郁症的患者以及创伤经历后1个月内纳入的患者中显示出增强的疗效。

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