Suppr超能文献

目前,对于有症状的颈内动脉狭窄,支架置入术并不比动脉内膜切除术更受青睐。

[Stenting of symptomatic stenosis of the internal carotid artery is not preferred over endarterectomy at this time].

作者信息

van der Worp H B, Kappelle L J

机构信息

Universitair Medisch Centrum Utrecht, Rudolf Magnus Instituut voor Neurowetenschappen, G03.228, Postbus 85.500, 3508 GA Utrecht.

出版信息

Ned Tijdschr Geneeskd. 2006 Nov 25;150(47):2582-5.

Abstract

Carotid endarterectomy reduces the risk of stroke in patients with symptomatic internal carotid-artery stenosis of 50% or greater. Carotid-artery stenting may be an attractive alternative. Two randomised trials comparing carotid endarterectomy with stenting have recently been terminated prematurely. Reasons for termination included an excess in stroke and death after stenting, compared with carotid endarterectomy (the EVA-3S trial) and futility reasons and the absence of funding (the SPACE trial). Given that both trials failed to prove the non-inferiority of stenting compared with carotid endarterectomy in the first 30 days, the use of stenting should be restricted to patients with contraindications to surgery and those participating in randomised clinical trials.

摘要

颈动脉内膜切除术可降低症状性颈内动脉狭窄达50%及以上患者的中风风险。颈动脉支架置入术可能是一种有吸引力的替代方法。最近两项比较颈动脉内膜切除术与支架置入术的随机试验均提前终止。终止的原因包括,与颈动脉内膜切除术相比,支架置入术后中风和死亡人数过多(EVA-3S试验),以及无效性原因和资金缺乏(SPACE试验)。鉴于这两项试验均未能在前30天内证明支架置入术不劣于颈动脉内膜切除术,支架置入术的应用应仅限于有手术禁忌证的患者以及参与随机临床试验的患者。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验