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[周围性面神经麻痹患者的临床分析]

[Clinical analysis of patients with peripheral facial palsy].

作者信息

Ilniczky Sándor

机构信息

Semmelweis Egyetem, Altalános Orvostudományi Kar, Neurológiai Klinika, Budapest.

出版信息

Ideggyogy Sz. 2006 Nov 20;59(11-12):400-5.

Abstract

UNLABELLED

Peripheral facial palsy is one of the most frequent neurological symptoms. In two thirds of the cases the cause is unknown, this is called "idiopathic peripheral facial palsy or Bell's palsy", but several different diseases have to be considered in the differential diagnosis. In this paper we reviewed the case histories of 110 patients treated for "peripheral facial palsy" in the Department of Neurology, Semmelweis University, Budapest in a five year period, 2000-2004. We studied the age, gender distribution, seasonal occurrence, comorbidities, sidedness, symptoms, circumstances of referral to the hospital, the initial diagnoses and therapeutic options. We also discuss the probable causes and consequences of diagnostic failures.

RESULTS

the proportion of males and females was equal. There was no considerable difference between sexes regarding age-distribution. Of the 110 patients 106 was diagnosed with idiopathic Bell's palsy, three cases with otic herpes zoster and one patient with Lyme disease. In our material, peripheral facial palsy was significantly more frequent in the cold period of late autumn, winter, and early spring. Diabetes mellitus and hypertension were more frequent than in the general population. 74% of the patients were admitted within two days from the onset of the symptoms. In 37% preliminary diagnosis was unavailable. In 15% cerebrovascular insult was the first, incorrect diagnosis, the correct diagnosis of "Bell's palsy" was provided only in 16%. The probable causes of diagnostic failures may be the misleading symptoms and accompanying conditions. We examined the different therapies applied and reviewed the literature in this topic. We conclude that intravenous corticosteroid treatment in the early stage of the disease is the therapy of choice.

摘要

未标注

周围性面瘫是最常见的神经系统症状之一。三分之二的病例病因不明,这被称为“特发性周围性面瘫或贝尔面瘫”,但在鉴别诊断中必须考虑几种不同的疾病。本文回顾了2000年至2004年期间在布达佩斯塞梅尔维斯大学神经病学系接受“周围性面瘫”治疗的110例患者的病历。我们研究了年龄、性别分布、季节发病情况、合并症、患侧、症状、转诊至医院的情况、初始诊断和治疗选择。我们还讨论了诊断失败的可能原因和后果。

结果

男性和女性比例相等。在年龄分布方面,两性之间没有显著差异。110例患者中,106例被诊断为特发性贝尔面瘫,3例为耳部带状疱疹,1例为莱姆病。在我们的资料中,周围性面瘫在深秋、冬季和早春的寒冷时期明显更常见。糖尿病和高血压比一般人群更常见。74%的患者在症状出现后两天内入院。37%的患者初步诊断不明确。15%的患者首先被误诊为脑血管病变,只有16%的患者被正确诊断为“贝尔面瘫”。诊断失败的可能原因可能是误导性症状和伴随情况。我们研究了所应用的不同治疗方法并回顾了该主题的文献。我们得出结论,在疾病早期静脉注射皮质类固醇治疗是首选治疗方法。

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