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[基于证据的带状疱疹后神经痛治疗与预防的有限可能性]

[Limited possibilities for the evidence-based treatment and prevention of postherpetic neuralgia].

作者信息

Zuurmond W W A, Perez R S G M

机构信息

VU Medisch Centrum, afd. Anesthesiologie, Postbus 7057, 1007 MB Amsterdam.

出版信息

Ned Tijdschr Geneeskd. 2006 Dec 2;150(48):2633-6.

Abstract

Postherpetic neuralgia is a disorder that occurs frequently in the elderly. As the effect of the treatment of postherpetic neuralgia is often disappointing, studies have focussed on the prevention of this complaint. A commonly used preventive intervention is the administration ofa single epidural injection of a local anaesthetic and a corticosteroid, combined with oral antiviral agents and analgesics. In a large, multicentre, randomised controlled trial, the investigators found that the single injection of a corticosteroid and a local anaesthetic had no added value in the prevention of long-term postherpetic neuralgia.

摘要

带状疱疹后神经痛是一种在老年人中频繁发生的疾病。由于带状疱疹后神经痛的治疗效果常常令人失望,研究已聚焦于预防这种病症。一种常用的预防性干预措施是单次硬膜外注射局部麻醉剂和皮质类固醇,并联合口服抗病毒药物和镇痛药。在一项大型、多中心、随机对照试验中,研究人员发现单次注射皮质类固醇和局部麻醉剂在预防长期带状疱疹后神经痛方面并无额外益处。

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