Chiba S, Muneoka Y, Miyagishi T, Tanaka T
Department of Psychiatry and Neurology, Asahikawa Medical College, Japan.
No To Shinkei. 1991 Sep;43(9):869-73.
We reported a 40-year-old right-handed female with temporal lobe epilepsy manifesting recurrent dysphasic seizures. At age 25, the patient developed a complex partial seizure, who subsequently showed frequent auditory seizures that often evolved to complex partial or secondarily generalized seizures at age 25-27, and dysphasic seizures (DSs) at age 27 -40. DSs were characterized by total aphasia without impairment of consciousness, which were often accompanied by functional hallucination. Brain CT, cerebral angiography, and brain MRI demonstrated no abnormal findings. At age 39 (May 20, 1989), recurrent aphasic state was unexpectedly observed during medical examinations. An EEG was performed immediately, and the EEG seizure pattern (duration: ca. 8-17 sec) in which 15 -16 Hz spikes began in the left posterior temporal region and spread rapidly to the left midtemporal, inferior frontal, and central regions was detected 14 times within 30 minutes. During the seizure patterns, the patient was aphasic.
我们报告了一名40岁右利手女性,患有颞叶癫痫,表现为反复发作的言语障碍性癫痫发作。患者25岁时出现复杂部分性发作,随后在25 - 27岁时频繁出现听觉发作,且常演变为复杂部分性发作或继发性全身性发作,27 - 40岁时出现言语障碍性发作(DSs)。DSs的特征是完全失语但意识无损害,常伴有功能性幻觉。脑部CT、脑血管造影和脑部MRI均未发现异常。39岁时(1989年5月20日),在体检期间意外观察到反复出现的失语状态。立即进行了脑电图检查,在30分钟内检测到14次脑电图癫痫发作模式(持续时间:约8 - 17秒),其中15 - 16Hz的棘波从左后颞区开始,迅速扩散到左中颞区、额下回和中央区。在癫痫发作模式期间,患者失语。