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香港儿童使用外用倍他米松治疗包茎的疗效及复发情况。

Outcome and recurrence in treatment of phimosis using topical betamethasone in children in Hong Kong.

作者信息

Ku Wai-Hung, Chiu Becky S-K, Huen Kwai-Fun

机构信息

Department of Paediatrics and Adolescent Medicine, Tseung Kwan O Hospital, Hong Kong SAR, China.

出版信息

J Paediatr Child Health. 2007 Jan-Feb;43(1-2):74-9. doi: 10.1111/j.1440-1754.2007.01006.x.

Abstract

AIM

To study the efficacy of treating phimosis with topical steroid, and its long-term outcome and side effects. We also looked into the effect of daily retraction and cleansing of prepuce on preventing recurrence of phimsosis.

METHODS

This prospective study comprised 138 boys who were prescribed 0.05% betamethasone ointment (Diprocel) during 1 August 2001-31 July 2004. Five boys were excluded because of non-compliance. Of the remaining 133 boys, 108 were followed-up and assessed. Age ranged from 0.03 to 12.9 years (mean=3.38, SD=2.79). The number of treatment course received, short-term and long-term outcome, side effects and the effect of daily foreskin retraction were studied.

RESULTS

The success rate of first treatment course was 81.5%, and 60.2% of boys remained free from phimosis upon latest assessment. The follow-up period ranged from 0.4 to 4.4 years (mean=2.45, SD=0.90). There were no side effects noted. We found a significant and linear relationship between daily foreskin retraction and sustained resolution of phimosis.

CONCLUSION

Topical steroid is an effective and safe treatment for phimosis, especially when combined with a good hygiene practice of the foreskin with daily cleansing and retraction. A trial of topical steroid treatment should be offered upon considering circumcision.

摘要

目的

研究局部使用类固醇治疗包茎的疗效、长期效果及副作用。我们还探讨了每日包皮上翻及清洗对预防包茎复发的作用。

方法

这项前瞻性研究纳入了138名在2001年8月1日至2004年7月31日期间使用0.05%倍他米松软膏(得宝松)的男孩。5名男孩因未遵从而被排除。在其余133名男孩中,108名接受了随访和评估。年龄范围为0.03至12.9岁(平均=3.38,标准差=2.79)。研究了接受的治疗疗程数量、短期和长期效果、副作用以及每日包皮上翻的作用。

结果

首个治疗疗程的成功率为81.5%,在最近一次评估时,60.2%的男孩无包茎复发。随访期为0.4至4.4年(平均=2.45,标准差=0.90)。未观察到副作用。我们发现每日包皮上翻与包茎的持续缓解之间存在显著的线性关系。

结论

局部使用类固醇是治疗包茎的一种有效且安全的方法,尤其是与每日清洗和上翻包皮的良好卫生习惯相结合时。在考虑包皮环切术时,应先尝试局部类固醇治疗。

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