Fusion of H4/D10S170 to PDGFRbeta in a patient with chronic myelomonocytic leukemia and long-term responsiveness to imatinib.

Suppr

超能文献

作者信息

Drechsler Matthias, Hildebrandt Barbara, Kündgen Andrea, Germing Ulrich, Royer-Pokora Brigitte

出版信息

Ann Hematol. 2007 May;86(5):353-4. doi: 10.1007/s00277-006-0247-5. Epub 2007 Jan 9.

DOI:10.1007/s00277-006-0247-5

PMID:17211520

Abstract

摘要

相似文献

Fusion of H4/D10S170 to PDGFRbeta in a patient with chronic myelomonocytic leukemia and long-term responsiveness to imatinib.

Ann Hematol. 2007 May;86(5):353-4. doi: 10.1007/s00277-006-0247-5. Epub 2007 Jan 9.

Trisomy 8 in PDGFRB-negative cells in a patient with imatinib-sensitive chronic myelomonocytic leukemia and t(5;16)(q33;p13), PDGFRB-NDE1 fusion.

Cancer Genet Cytogenet. 2009 Oct;194(1):67-9. doi: 10.1016/j.cancergencyto.2009.04.026.

Sensitivity to imatinib but low frequency of the TEL/PDGFRbeta fusion protein in chronic myelomonocytic leukemia.

Haematologica. 2003 Apr;88(4):408-15.

Response to STI571 in chronic myelomonocytic leukemia with platelet derived growth factor beta receptor involvement: a new case report.

Haematologica. 2003 May;88(5):ECR18.

Imatinib mesylate therapy in chronic myeloid leukaemia: the floodgates opened.

J Assoc Physicians India. 2007 Feb;55:99-100.

Identification of a MYO18A-PDGFRB fusion gene in an eosinophilia-associated atypical myeloproliferative neoplasm with a t(5;17)(q33-34;q11.2).

Genes Chromosomes Cancer. 2009 Feb;48(2):179-83. doi: 10.1002/gcc.20629.

Sustained response to low-dose imatinib mesylate in a patient with chronic myelomonocytic leukemia with t(5;12)(q33;p13).

Acta Haematol. 2008;119(1):57-9. doi: 10.1159/000115966. Epub 2008 Feb 12.

Lack of response to imatinib mesylate in a patient with accelerated phase myeloproliferative disorder with rearrangement of the platelet-derived growth factor receptor beta-gene.

Haematologica. 2004 Oct;89(10):1263-4.

TV6 and PDGFRB: a license to fuse.

Haematologica. 2007 Feb;92(2):145-7. doi: 10.3324/haematol.11187.

Long-term experience with imatinib therapy in chronic phase chronic myelogenous leukemia--remarkable activity with room for improvement.

Am J Hematol. 2008 Mar;83(3):175-7. doi: 10.1002/ajh.21136.

引用本文的文献

Genetic fusions favor tumorigenesis through degron loss in oncogenes.

Nat Commun. 2021 Nov 18;12(1):6704. doi: 10.1038/s41467-021-26871-y.

NSCLC Mutated Isoforms of CCDC6 Affect the Intracellular Distribution of the Wild Type Protein Promoting Cisplatinum Resistance and PARP Inhibitors Sensitivity in Lung Cancer Cells.

Cancers (Basel). 2019 Dec 21;12(1):44. doi: 10.3390/cancers12010044.

Myeloid/Lymphoid Neoplasm with PDGFRB Rearrangement with t (5;10) (q33;q22) Harboring a Novel Breakpoint of the CCDC6-PDGFRB Fusion Gene.

Intern Med. 2019 Dec 1;58(23):3449-3453. doi: 10.2169/internalmedicine.3220-19. Epub 2019 Jul 22.

Proposed diagnostic criteria for classical chronic myelomonocytic leukemia (CMML), CMML variants and pre-CMML conditions.

Haematologica. 2019 Oct;104(10):1935-1949. doi: 10.3324/haematol.2019.222059. Epub 2019 May 2.

The rationale for druggability of CCDC6-tyrosine kinase fusions in lung cancer.

Mol Cancer. 2018 Feb 19;17(1):46. doi: 10.1186/s12943-018-0799-8.

FBXW7 and USP7 regulate CCDC6 turnover during the cell cycle and affect cancer drugs susceptibility in NSCLC.

Oncotarget. 2015 May 20;6(14):12697-709. doi: 10.18632/oncotarget.3708.

Discovery of imatinib-responsive FIP1L1-PDGFRA mutation during refractory acute myeloid leukemia transformation of chronic myelomonocytic leukemia.

J Hematol Oncol. 2014 Mar 27;7:26. doi: 10.1186/1756-8722-7-26.

Identification of sumoylation sites in CCDC6, the first identified RET partner gene in papillary thyroid carcinoma, uncovers a mode of regulating CCDC6 function on CREB1 transcriptional activity.

PLoS One. 2012;7(11):e49298. doi: 10.1371/journal.pone.0049298. Epub 2012 Nov 7.

Loss of CCDC6, the first identified RET partner gene, affects pH2AX S139 levels and accelerates mitotic entry upon DNA damage.

PLoS One. 2012;7(5):e36177. doi: 10.1371/journal.pone.0036177. Epub 2012 May 24.

Loss of CCDC6 affects cell cycle through impaired intra-S-phase checkpoint control.

PLoS One. 2012;7(2):e31007. doi: 10.1371/journal.pone.0031007. Epub 2012 Feb 17.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验