与PHACE综合征相关的颅内婴儿血管瘤。
Intracranial infantile hemangiomas associated with PHACE syndrome.
作者信息
Judd C D, Chapman P R, Koch B, Shea C J
机构信息
Inland Imaging, Spokane, Washington 99202, USA.
出版信息
AJNR Am J Neuroradiol. 2007 Jan;28(1):25-9.
BACKGROUND AND PURPOSE
Head and neck infantile hemangiomas are common lesions that are rarely observed in an intracranial location. We report 4 patients with orbital infantile hemangiomas and ipsilateral enhancing intracranial lesions, presumed to be infantile hemangiomas.
METHODS
Imaging studies and medical records of 4 infants with orbital hemangiomas and enhancing intracranial lesions were reviewed. The intracranial lesions were evaluated in terms of their location, signal intensity characteristics, enhancement pattern, and degree of involution following treatment. Additional findings associated with PHACE syndrome were also noted and a literature review of intracranial infantile hemangiomas and PHACE syndrome was also performed.
RESULTS
The intracranial masses were primarily in or adjacent to the internal auditory canal and demonstrated imaging characteristics and treatment response similar to the ipsilateral orbital lesions. Ipsilateral internal carotid artery hypoplasia, ipsilateral cerebellar hemisphere hypoplasia, and/or other head and neck hemangiomas were present in all patients.
CONCLUSION
These cases collectively support the diagnosis of intracranial infantile hemangiomas and suggest a unique radiographic association between PHACE syndrome and intracranial infantile hemangiomas.
背景与目的
头颈部婴幼儿血管瘤是常见病变，但很少见于颅内。我们报告4例患有眼眶婴幼儿血管瘤及同侧强化颅内病变的患者，推测为婴幼儿血管瘤。
方法
回顾了4例患有眼眶血管瘤及强化颅内病变的婴儿的影像学研究和病历。对颅内病变的位置、信号强度特征、强化模式及治疗后的消退程度进行了评估。还记录了与PHACE综合征相关的其他发现，并对颅内婴幼儿血管瘤和PHACE综合征进行了文献综述。
结果
颅内肿块主要位于内耳道内或其附近，其影像学特征及治疗反应与同侧眼眶病变相似。所有患者均存在同侧颈内动脉发育不全、同侧小脑半球发育不全和/或其他头颈部血管瘤。
结论
这些病例共同支持颅内婴幼儿血管瘤的诊断，并提示PHACE综合征与颅内婴幼儿血管瘤之间存在独特的影像学关联。
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