半乳糖凝集素-3在小鼠各种组织中的表达及免疫组化定位
Expression and immunohistochemical localization of galectin-3 in various mouse tissues.
作者信息
Kim Heechul, Lee Jeeyoung, Hyun Jin Won, Park Jae Woo, Joo Hong-gu, Shin Taekyun
机构信息
Department of Veterinary Medicine, Cheju National University, Jeju 690-756, South Korea.
出版信息
Cell Biol Int. 2007 Jul;31(7):655-62. doi: 10.1016/j.cellbi.2006.11.036. Epub 2006 Dec 5.
The expression and immunohistochemical localization of galectin-3, a beta-galactoside-binding protein, was studied in several mouse tissues. Galectin-3 expression was low in the cerebrum, heart, and pancreas, and moderate in the liver, ileum, kidney, and adrenal gland. High expression of galectin-3 was found in the lung, spleen, stomach, colon, uterus, and ovary. The results of Western blot analysis largely matched the immunohistochemical findings for galectin-3. These findings suggest that galectin-3 is differentially expressed in a variety of organs in the mouse. This study provides valuable information for research on galectin-3.
对一种β-半乳糖苷结合蛋白——半乳糖凝集素-3在几种小鼠组织中的表达及免疫组化定位进行了研究。半乳糖凝集素-3在大脑、心脏和胰腺中表达较低，在肝脏、回肠、肾脏和肾上腺中表达中等。在肺、脾脏、胃、结肠、子宫和卵巢中发现半乳糖凝集素-3高表达。蛋白质免疫印迹分析结果与半乳糖凝集素-3的免疫组化结果基本相符。这些发现表明半乳糖凝集素-3在小鼠的多种器官中存在差异表达。本研究为半乳糖凝集素-3的研究提供了有价值的信息。
Zotero 插件