系上联结的纽带。

Tying the knot that binds.

作者信息

Gloss Lisa M

机构信息

School of Molecular Biosciences, Washington State University, Pullman, WA 99164, USA.

出版信息

Structure. 2007 Jan;15(1):2-4. doi: 10.1016/j.str.2006.12.001.

DOI:10.1016/j.str.2006.12.001

PMID:17223526

Abstract

The recent determination of protein structures with knots in their backbone topology has defied previous conventional wisdom. How proteins can fold with a knot is an intriguing question that has been explored for YibK from Haemophilus influenzae in this issue of Structure.

摘要

最近对具有打结主链拓扑结构的蛋白质结构的测定颠覆了以往的传统认知。蛋白质如何带着结进行折叠是一个引人入胜的问题，在本期《结构》杂志中针对来自流感嗜血杆菌的YibK蛋白进行了探索。