Saad Fairouz, Revdal Hege, Aldrich Tim E
Department of Epidemiology and Clinical Investigation Sciences, University of Louisville, School of Public Health and Information Sciences, 555 So. Floyd Street K- Bldg. Suite 345, Louisville, KY 40202 , USA.
J Ky Med Assoc. 2006 Dec;104(12):553-9.
Comparisons were made for unstaged lung cancer cases both to "staged" lung cancer cases and to unstaged cases from all other sites, in Kentucky for 1996-2000. Principal findings were that the likelihood of the lung cancer cases to be unstaged was greater when the cancer incidence report came from sources other than a hospital. This may implicate data system forces [for availability of necessary data for completing stage at diagnosis] rather than differences between cases per se. The risk of being unstaged by smoking status was reversed between lung cancer (lower risk) than for all other cancer sites (higher risk), an unexpected pattern. No difference for survival was found for unstaged versus staged lung cancer cases, as well as no differences for race and gender. The finding of no differences suggests that other forces (eg, age, source of payment) may contribute more greatly to one's likelihood of being unstaged with a diagnosis of lung cancer than for "all other cancer sites." These patterns pose provocative implications for how smoking status may influence clinical perspectives and those of persons faced with a diagnosis of cancer.
对1996 - 2000年肯塔基州未分期肺癌病例与“分期”肺癌病例以及所有其他部位的未分期病例进行了比较。主要发现是,当癌症发病率报告来自医院以外的来源时,肺癌病例未分期的可能性更大。这可能意味着数据系统因素[用于获取诊断时完成分期所需的必要数据],而非病例本身之间的差异。按吸烟状况划分的未分期风险在肺癌(风险较低)和所有其他癌症部位(风险较高)之间呈现相反情况,这是一种意外模式。未发现未分期肺癌病例与分期肺癌病例在生存率上存在差异,在种族和性别方面也没有差异。未发现差异这一结果表明,与“所有其他癌症部位”相比,其他因素(如年龄、支付来源)可能对肺癌诊断时未分期的可能性影响更大。这些模式对吸烟状况如何影响临床观点以及面临癌症诊断的人群的观点具有启发性意义。