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腰围作为老年人残疾的预测指标。

Waist circumference as a predictor of disability among older adults.

作者信息

Guallar-Castillón Pilar, Sagardui-Villamor Jon, Banegas José R, Graciani Auxiliadora, Fornés Nélida Schmid, López García Esther, Rodríguez-Artalejo Fernando

机构信息

Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain.

出版信息

Obesity (Silver Spring). 2007 Jan;15(1):233-44. doi: 10.1038/oby.2007.532.

Abstract

OBJECTIVE

Few studies have addressed the association between abdominal obesity, as measured by waist circumference (WC), and disability in the elderly. Moreover, those studies were cross-sectional and yielded inconsistent results. The objective of this study was to examine longitudinally the association between WC and self-reported disability among older adults.

RESEARCH METHODS AND PROCEDURES

A prospective cohort study was conducted from 2001 to 2003 in 3235 persons (1411 men and 1824 women) representative of the non-institutionalized Spanish population ages 60 years and older. Baseline information was collected by home-based personal interviews and measurement of WC, weight, and height. Two years later, information on disability was obtained by telephone interview. The association of interest was summarized with odds ratios obtained by logistic regression.

RESULTS

Among persons reporting no disability at baseline, WC predicted disability 2 years later. After adjustment for age, education, tobacco use, alcohol consumption, and physical activity, men in the highest WC quintile had 2.17 (95% confidence interval, 1.15 to 4.09) times more risk of mobility disability and 4.77 (95% confidence interval, 2.50 to 9.13) times more risk of agility disability than those in the lowest quintile. Additional adjustment for BMI, chronic diseases, and cognitive function led to only a slight reduction in this association. Results were similar for women. No statistically significant association was observed between WC and restriction of daily activities, limitation in instrumental activities of daily living, and limitation in bathing or dressing, in either men or women.

DISCUSSION

WC predicts mobility and agility disability in old age. Avoidance of the highest values of WC might decrease the risk of disability in older adults.

摘要

目的

很少有研究探讨以腰围(WC)衡量的腹部肥胖与老年人残疾之间的关联。此外,这些研究均为横断面研究,结果并不一致。本研究的目的是纵向考察老年人中WC与自我报告的残疾之间的关联。

研究方法与步骤

2001年至2003年对3235名(1411名男性和1824名女性)60岁及以上非机构化西班牙人群的代表性样本进行了一项前瞻性队列研究。通过上门入户的个人访谈收集基线信息,并测量WC、体重和身高。两年后,通过电话访谈获取残疾信息。通过逻辑回归得到的比值比总结了感兴趣的关联。

结果

在基线时报告无残疾的人群中,WC可预测两年后的残疾情况。在调整了年龄、教育程度、吸烟、饮酒和身体活动后,WC最高五分位数组的男性发生行动不便残疾的风险是最低五分位数组男性的2.17倍(95%置信区间为1.15至4.09),发生敏捷性残疾的风险是其4.77倍(95%置信区间为2.50至9.13)。进一步调整体重指数(BMI)、慢性病和认知功能后,这种关联仅略有减弱。女性的结果相似。在男性和女性中,均未观察到WC与日常活动受限、工具性日常生活活动受限以及洗澡或穿衣受限之间存在统计学显著关联。

讨论

WC可预测老年时的行动不便和敏捷性残疾。避免WC达到最高值可能会降低老年人残疾的风险。

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