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[短暂性颈动脉缺血性发作:临床与发病机制方面]

[Transitory carotid ischemic attacks: clinical and pathogenic aspects].

作者信息

Fiorini E, Regli F, Bogousslavsky J

机构信息

Service de neurologie, Centre hospitalier universitaire vaudois, Lausanne.

出版信息

Schweiz Arch Neurol Psychiatr (1985). 1991;142(6):485-98.

PMID:1722904
Abstract

The aim of this study is to describe the clinical characteristics and the pathological mechanisms of carotid transient ischemic attacks (TIA) in 117 patients which were hospitalised for such symptoms. Our results show a male predominance, except for age group under 40 and over 79 years. The principal cardiovascular index and risk factors are: arterial hypertension, smoking, hyperlipidemia, vascular intermittent claudication and hematocrit greater than 46%. Amongst our patients, 17% with hemispherical and mixed TIAs had a cerebral infarction proved by CT-Scan, the recent aspect and localisation of which were compatible with symptoms. The atherosclerotic causes are more frequently associated with mixed and retinal TIAs than hemispheric TIAs. This fact may be attributed to a larger proportion of stenotic atherosclerotic lesions by mixed TIAs than hemispheric ones. The cardiac embolic pathogenic mechanism is responsible for 11% of TIAs if considered individually; of 5% if associated with carotid atherosclerosis.

摘要

本研究的目的是描述117例因颈动脉短暂性脑缺血发作(TIA)症状入院患者的临床特征和病理机制。我们的结果显示,除了40岁以下和79岁以上年龄组外,男性占主导。主要的心血管指标和危险因素为:动脉高血压、吸烟、高脂血症、血管间歇性跛行和血细胞比容大于46%。在我们的患者中,17%的半球性和混合性TIA患者经CT扫描证实有脑梗死,其近期表现和定位与症状相符。动脉粥样硬化病因与混合性和视网膜性TIA的关联比半球性TIA更常见。这一事实可能归因于混合性TIA比半球性TIA有更大比例的狭窄性动脉粥样硬化病变。心脏栓塞致病机制单独考虑时占TIA的11%;与颈动脉粥样硬化相关时占5%。

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