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1例膀胱原发性黏膜相关淋巴组织淋巴瘤在利妥昔单抗联合CHOP化疗后病情缓解

[A case of primary mucosa-associated lymphoid tissue lymphoma of the bladder regressed after rituximab in combination with CHOP chemotherapy].

作者信息

Kakuta Yoichi, Katoh Taigo, Saitoh Jun, Yazawa Kohji, Hosomi Masahiro, Itoh Kiichiro

机构信息

Department of Urology, Osaka General Medical Center.

出版信息

Hinyokika Kiyo. 2006 Dec;52(12):951-4.

Abstract

Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the bladder is a rare disease, and the most effective therapeutic procedure remains unknown. We report a case of primary MALT lymphoma of the bladder regressed after rituximab in combination with CHOP chemotherapy (R-CHOP). The patient, a 84-year-old woman, presented with general fatigue and loss of weight. Computed tomography (CT) showed a solitary mass at the bladder. Histological diagnosis of the tissue obtained by transurethral biopsy was extranodal marginal zone B cell lymphoma of MALT. The patient was in complete remission after only one cycle of R-CHOP. This is the fourteenth case of MALT lymphoma of the bladder in Japan.

摘要

原发性膀胱黏膜相关淋巴组织(MALT)淋巴瘤是一种罕见疾病,最有效的治疗方法仍不明确。我们报告一例原发性膀胱MALT淋巴瘤患者在接受利妥昔单抗联合CHOP化疗(R-CHOP)后病情缓解。该患者为一名84岁女性,表现为全身乏力和体重减轻。计算机断层扫描(CT)显示膀胱有一个孤立性肿块。经尿道活检获取的组织的组织学诊断为MALT型结外边缘区B细胞淋巴瘤。该患者仅接受一个周期的R-CHOP治疗后即完全缓解。这是日本第14例膀胱MALT淋巴瘤病例。

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