Schmitz S, Weynand B, Lengelé B, Hamoir M
Department of Oto-Rhino-Laryngology and Head and Neck Surgery, St-Luc University Hospital, Brussels, Belgium.
B-ENT. 2006;2(4):201-4.
Solitary fibrous tumour (SFT) is a rare mesenchymal neoplasm described first in the pleura. Recently, SFTs have been found in various extra-serosal locations, including the head and neck region.
We report a case of SFT originating from the periorbital region of the face. Preoperative cytological examination by fine needle aspiration biopsy diagnosed a mesenchymal tumour. The patient underwent surgical resection. The mass was completely resected. Definitive histopathologic and immunohistologic examination confirmed the diagnosis of SFT.
The rare localisation in extrapleural sites and the multiplicity of histological patterns can explain the difficulty in arriving at a definitive diagnosis in SFT. Usually, SFT is a benign tumour, although malignant variants exist. Clinical behaviour is unpredictable and recurrence or malignant transformation can also occur, especially in cases with macroscopically or microscopically invaded margins. Complete surgical excision and long follow-up is therefore always recommended. The recent increase in reports of extrapleural SFT indicates that this rare tumour should be included in the differential diagnosis of soft tissue head and neck tumours.
孤立性纤维瘤(SFT)是一种罕见的间叶性肿瘤,最初在胸膜中被描述。最近,SFT在包括头颈部区域在内的各种浆膜外部位被发现。
我们报告一例起源于面部眶周区域的SFT病例。术前通过细针穿刺活检进行的细胞学检查诊断为间叶性肿瘤。患者接受了手术切除。肿块被完全切除。最终的组织病理学和免疫组织化学检查证实了SFT的诊断。
浆膜外部位的罕见定位以及组织学模式的多样性可以解释SFT难以做出明确诊断的原因。通常,SFT是一种良性肿瘤,尽管存在恶性变体。临床行为不可预测,也可能发生复发或恶性转化,尤其是在宏观或微观边缘受侵的病例中。因此,始终建议进行完整的手术切除并长期随访。最近浆膜外SFT报告的增加表明,这种罕见肿瘤应纳入头颈部软组织肿瘤的鉴别诊断中。