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儿童化脓性髋关节败血症的前瞻性研究。

A prospective study of pyogenic sepsis of the hip in childhood.

作者信息

Nunn T R, Cheung W Y, Rollinson P D

机构信息

Huddersfield Royal Infirmary, Acre Mill, Lindley, Huddersfield, UK.

出版信息

J Bone Joint Surg Br. 2007 Jan;89(1):100-6. doi: 10.1302/0301-620X.89B1.17940.

Abstract

Between September 2004 and December 2005 we carried out a prospective study of all cases of sepsis of the hip in childhood at a South African regional hospital with a large local population, and which also took referrals from nine rural hospitals. The clinical, radiological, ultrasound and bacteriological features were assessed. All the hips were drained by arthrotomy and the diagnosis was confirmed microbiologically and histologically. Hips with tuberculosis were excluded. The children were reviewed in a dedicated clinic at a mean follow-up of 8.1 months (3 to 18). There were 40 hips with sepsis in 38 patients. Two patients were lost to follow-up. Nine (24%) had multi-focal sepsis. Overall, 13 hips (34%) had a full and uncomplicated clinical and radiological recovery and 25 (66%) had complications. All patients treated by arthrotomy and appropriate antibiotics within five days of the onset of symptoms had an uncomplicated recovery. Initial misdiagnosis was associated with a delay to arthrotomy. However, 'deprivation', consultation with a traditional healer, maternal educational attainment and distance to a primary health-care facility were not associated with delay to arthrotomy. The early correct diagnosis of this condition, common in the developing world, remains a significant factor in improving the clinical outcome.

摘要

2004年9月至2005年12月期间,我们在一家南非地区医院对所有儿童髋关节脓毒症病例进行了一项前瞻性研究。该医院当地人口众多,还接收来自9家乡村医院的转诊患者。我们评估了临床、放射学、超声和细菌学特征。所有髋关节均通过关节切开引流,诊断通过微生物学和组织学得到证实。排除患有结核病的髋关节。在一个专门的诊所对儿童进行了复查,平均随访时间为8.1个月(3至18个月)。38例患者中有40个髋关节发生脓毒症。2例患者失访。9例(24%)患有多灶性脓毒症。总体而言,13个髋关节(34%)实现了完全且无并发症的临床和放射学恢复,25个(66%)出现了并发症。所有在症状出现后5天内接受关节切开术和适当抗生素治疗的患者均实现了无并发症的恢复。最初的误诊与关节切开术的延迟有关。然而,“贫困”、咨询传统治疗师、母亲的教育程度以及到初级卫生保健机构的距离与关节切开术的延迟无关。在发展中国家常见的这种疾病的早期正确诊断,仍然是改善临床结果的一个重要因素。

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