核边界内外转录因子的分裂人格

Split personality of transcription factors inside and outside the nuclear border.

作者信息

Naranjo José R, Mellström Britt

机构信息

Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Cientificas, Madrid, Spain.

出版信息

Sci STKE. 2007 Jan 30;2007(371):pe5. doi: 10.1126/stke.3712007pe5.

DOI:10.1126/stke.3712007pe5

PMID:17264316

Abstract

Growing evidence indicates that transcription factors may have functions entirely distinct from the regulation of gene transcription. Here we describe three transcription factors that, when outside the nucleus, regulate calcium homeostasis by three independent but convergent mechanisms.

摘要

越来越多的证据表明，转录因子可能具有与基因转录调控完全不同的功能。在此，我们描述了三种转录因子，它们在细胞核外时，通过三种独立但趋同的机制调节钙稳态。