Ellabib M S, Khalifa Z M
Department of Medical Microbiology, Medical College, El-Fateh University, Tripoli, Libya.
Ann Saudi Med. 2001 May-Jul;21(3-4):193-5. doi: 10.5144/0256-4947.2001.193.
Our objective in this study was to obtain information on the prevalence of fungi responsible for superficial mycoses in the region of Tripoli, Libya.
Skin scrapings collected from 2224 patients attending the Dermatology Clinic at Tripoli Medical Center with suspected clinical symptoms of fungal involvement were investigated in a 28-month study period, from August 1997 to December 1999. Direct microscopy was carried out with a 20% KOH preparation, and cultures were performed in petri dishes on Sabouraud dextrose agar (SDA) with cycloheximide 0.5 mg/mL and chloramphenicol 0.05 mg/mL, and SDA with chloramphenicol 0.05 mg/mL. Olive oil (2%) was added to the SDA without cycloheximide when pityriasis versicolor was suspected.
Diagnosis was confirmed by microscopic examination in 1180 cases (53.1%), and the causal agents were isolated in 1160 cases (52.2%). Dermatophytes, Malassezia furfur (tinea versicolor) and Candida albicans were the major etiological agents isolated. Tinea corporis accounted for 45.9% (85% occurred in children below 15 years of age). The frequency of other clinical types in descending order was pityriasis versicolor 27.8% (322 cases), candidosis 13.4% (156 cases), tinea pedis 8.1% (94 cases), tinea manuum 2.6% (30 cases), and tinea barbae 2.2% (26 cases). Trichophyton violaceum was the most common etiological agent, and was responsible for 44% (300 cases) of dermatophyte infections. Malassezia furfur was ranked second in frequency with 27.8% (322 cases), followed by Trichophyton rubrum 13.8% (160 cases), and Candida albicans 10% (116 cases). Other species found were Microsporum canis 8.1% (94 cases), Epidermophyton floccosum 6.6% (76 cases), and Trichophyton mentagrophytes 3.1% (36 cases).
Dermatophytes, in particular Trichophyton violaceum, Trichophyton rubrum and Microsporum canis, are an important cause of tinea corporis in Libya. Malassezia furfur and Candida albicans are the most commonly encountered fungi in superficial mycoses.
本研究的目的是获取有关利比亚的黎波里地区引起浅表真菌病的真菌流行情况的信息。
在1997年8月至1999年12月的28个月研究期间，对的黎波里医疗中心皮肤科诊所2224例有疑似真菌累及临床症状的患者采集的皮肤刮屑进行了调查。用20%氢氧化钾制剂进行直接显微镜检查，并在含有0.5mg/mL环己酰亚胺和0.05mg/mL氯霉素的沙氏葡萄糖琼脂（SDA）平板以及含有0.05mg/mL氯霉素的SDA上进行培养。当怀疑有花斑癣时，向不含环己酰亚胺的SDA中添加2%橄榄油。
1180例（53.1%）通过显微镜检查确诊，1160例（52.2%）分离出病原体。皮肤癣菌、糠秕马拉色菌（花斑癣）和白色念珠菌是分离出的主要病原体。体癣占45.9%（85%发生在15岁以下儿童）。其他临床类型的频率由高到低依次为花斑癣27.8%（322例）、念珠菌病13.4%（156例）、足癣8.1%（94例）、手癣2.6%（30例）和须癣2.2%（26例）。紫色毛癣菌是最常见的病原体，占皮肤癣菌感染的44%（300例）。糠秕马拉色菌的频率排名第二，为27.8%（322例），其次是红色毛癣菌13.8%（160例）和白色念珠菌10%（116例）。发现的其他菌种有犬小孢子菌8.1%（94例）、絮状表皮癣菌6.6%（76例）和须癣毛癣菌3.1%（36例）。
皮肤癣菌，尤其是紫色毛癣菌、红色毛癣菌和犬小孢子菌，是利比亚体癣的重要病因。糠秕马拉色菌和白色念珠菌是浅表真菌病中最常见的真菌。
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