Tan Juay-Seng, Bailey Christopher S, Dvorak Marcel F, Fisher Charles G, Cripton Peter A, Oxland Thomas R
Department of Mechanical Engineering, University of British Columbia, Canada.
Spine (Phila Pa 1976). 2007 Feb 1;32(3):334-41. doi: 10.1097/01.brs.0000253645.24141.21.
An in vitro cadaveric study comparing cage-vertebra interface strengths for 3 different screw-cement configurations.
To determine the effects of cement augmentation of pedicle screws on cage-vertebra interface failure properties for 2 interbody device shapes (elliptical or cloverleaf); and to compare between pedicle and anterior vertebral body screws with cement augmentation.
Pedicle or anterior screw fixation is commonly used with interbody device fixation. Cement has recently been shown to augment screw fixation in the osteoporotic spine by improving the screw-bone interface strength. The effect of cement augmentation of pedicle or anterior screws on cage-vertebra interface properties has not been previously studied or compared.
An elliptical or a cloverleaf-shaped indentor covering 40% of the endplate was axially compressed against the superior endplate of 48 thoracolumbar vertebrae. Each vertebra had polymethylmethacrylate cement augmentation of 1) anterior screws, 2) pedicle screws, or 3) pedicle screws without cement. Compressive load was applied through a mechanism that allowed unconstrained rotation of the indentors.
Cement augmentation of pedicle screws resulted in significantly higher failure loads (54%) and failure strength (69%) for both shaped indentors when compared with uncemented pedicle screws. There was no significant difference in failure load and failure strength between pedicle and anterior screws with cement augmentation. Indentor shape was not a significant factor on failure load or failure strength.
Cage-vertebra interface properties were improved when cement was used to augment vertebral and pedicle screws. Cement augmentation of pedicle or anterior screws may reduce interbody device subsidence.
一项体外尸体研究,比较3种不同螺钉 - 骨水泥配置下的椎间融合器 - 椎体界面强度。
确定骨水泥增强椎弓根螺钉对两种椎间融合器形状(椭圆形或苜蓿叶形)的椎间融合器 - 椎体界面失效特性的影响;并比较骨水泥增强的椎弓根螺钉与椎体前路螺钉。
椎弓根或前路螺钉固定常用于椎间融合器固定。最近有研究表明,骨水泥可通过提高螺钉 - 骨界面强度来增强骨质疏松性脊柱中的螺钉固定。此前尚未研究或比较过骨水泥增强椎弓根或前路螺钉对椎间融合器 - 椎体界面特性的影响。
将覆盖40%终板的椭圆形或苜蓿叶形压头轴向压在48个胸腰椎椎体的上终板上。每个椎体分别进行以下操作:1)椎体前路螺钉用聚甲基丙烯酸甲酯骨水泥增强;2)椎弓根螺钉用骨水泥增强;3)椎弓根螺钉不用骨水泥。通过允许压头无约束旋转的机制施加压缩载荷。
与未用骨水泥的椎弓根螺钉相比,骨水泥增强的椎弓根螺钉在两种形状的压头测试中均导致显著更高的失效载荷(54%)和失效强度(69%)。骨水泥增强的椎弓根螺钉和椎体前路螺钉在失效载荷和失效强度上无显著差异。压头形状对失效载荷或失效强度不是一个显著因素。
当使用骨水泥增强椎体和椎弓根螺钉时,椎间融合器 - 椎体界面特性得到改善。骨水泥增强椎弓根或前路螺钉可能会减少椎间融合器下沉。