Lasmar Laura Maria de Lima Belizario Facury, Camargos Paulo Augusto Moreira, Goulart Eugênio Marcos Andrade, Sakurai Emília
Pediatrics Department, Universidade Federal de Minas Gerais, School of Medicine, Belo Horizonte, Brazil.
J Bras Pneumol. 2006 Sep-Oct;32(5):391-9.
To determine the influence that hospital admission of suckling infants with asthma has on their risk for future admissions for the same cause.
A retrospective study was conducted, in which the charts of 202 patients, all less than fifteen years of age, were evaluated. All of the patients had been treated as outpatients in a pediatric pulmonology clinic and had been admitted to the hospital on one or more occasions. A multivariate analysis was conducted in order to evaluate the risk factors associated with multiple hospitalizations.
Virtually all of the patients evaluated were hospitalized a second time within 18 months of the first hospitalization. Among the patients first hospitalized at = 12 months of age, the second admission occurred sooner than did that recorded for those first hospitalized at > 12 months of age (p = 0.001). The risk factors found to be associated with multiple hospital admissions were as follows: age at first admission = 12 months (odds ratio: 2.55; 95% confidence interval: 1.18-5.48); age at first admission between 13 and 24 months (odds ratio: 3.54; 95% confidence interval: 1.31-9.63); and severity of asthma symptoms (odds ratio: 3.86; 95% confidence interval: 2.02-7.40).
After the first hospitalization, children with asthma should be closely monitored, since the risk of subsequent admissions is elevated in the first months following discharge, especially among those of less than two years of age. Health care facilities should be organized to confront this problem appropriately and should dispense prophylactic medication more freely.
确定哮喘哺乳婴儿住院对其未来因同一原因再次住院风险的影响。
进行了一项回顾性研究,评估了202例年龄均小于15岁患者的病历。所有患者均在儿科肺病门诊接受过门诊治疗,并曾一次或多次住院。进行多变量分析以评估与多次住院相关的危险因素。
几乎所有接受评估的患者在首次住院后的18个月内再次住院。在首次住院年龄≤12个月的患者中,第二次住院比首次住院年龄>12个月的患者更早发生(p = 0.001)。发现与多次住院相关的危险因素如下:首次住院年龄≤12个月(比值比:2.55;95%置信区间:1.18 - 5.48);首次住院年龄在13至24个月之间(比值比:3.54;95%置信区间:1.31 - 9.63);以及哮喘症状的严重程度(比值比:3.86;95%置信区间:2.02 - 7.40)。
首次住院后,哮喘儿童应密切监测,因为出院后的头几个月内再次住院的风险会升高,尤其是两岁以下的儿童。应合理组织医疗保健机构来应对这一问题,并应更自由地发放预防性药物。