Gong Edward M, Orvieto Marcelo A, Lyon Mark B, Lucioni Alvaro, Gerber Glenn S, Shalhav Arieh L
Department of Surgery, Section of Urology, University of Chicago Pritzker School of Medicine, Chicago, Illinois 60637, USA.
Urology. 2007 Jan;69(1):38-43. doi: 10.1016/j.urology.2006.09.020.
As the prevalence of obesity increases in the United States, it has become more important to assess its impact on surgical outcomes. We evaluated the significance of obesity on laparoscopic radical nephrectomy (LRN) and laparoscopic partial nephrectomy (LPN).
This was a prospective database study evaluating patients who underwent either LRN or LPN from October 2002 to January 2006. Patients were divided into five groups as determined by the World Health Organization body mass index (BMI) classification: less than 25.0, 25.0 to 29.9, 30.0 to 34.9, 35.0 to 39.9, and 40.0 kg/m2 or more. Demographic (age, tumor size, American Society for Anesthesiologists score), operative (estimated blood loss, operative time, open conversion), and postoperative (complications, hospital stay, margin status) data were compared.
Of 239 patients who had undergone LRN or LPN during the study period, 146 underwent LRN and 85 underwent LPN. Of the 239 patients, 42% were obese. No statistical significance was determined for estimated blood loss, operative time, hospital stay, number of open conversions, or complications. However, a trend toward increased operative time and intraoperative complications was determined using linear and logistic regression analyses.
Laparoscopic renal surgery is safe in overweight and obese patients and may be the surgical management of choice in this subset of patients. However, obese patients should be warned that their degree of obesity may be associated with increased difficulty of surgery as reflected by a trend toward longer operative times and more intraoperative complications.
随着美国肥胖症患病率的上升,评估其对外科手术结局的影响变得越发重要。我们评估了肥胖对腹腔镜根治性肾切除术(LRN)和腹腔镜部分肾切除术(LPN)的意义。
这是一项前瞻性数据库研究,评估了2002年10月至2006年1月期间接受LRN或LPN手术的患者。根据世界卫生组织体重指数(BMI)分类,患者被分为五组:小于25.0、25.0至29.9、30.0至34.9、35.0至39.9以及40.0kg/m²或更高。比较了人口统计学数据(年龄、肿瘤大小、美国麻醉医师协会评分)、手术数据(估计失血量、手术时间、中转开腹)和术后数据(并发症、住院时间、切缘状态)。
在研究期间接受LRN或LPN手术的239例患者中,146例接受了LRN,85例接受了LPN。在这239例患者中,42%为肥胖患者。在估计失血量、手术时间、住院时间、中转开腹次数或并发症方面未确定统计学意义。然而,通过线性和逻辑回归分析确定了手术时间和术中并发症增加的趋势。
腹腔镜肾手术在超重和肥胖患者中是安全的,可能是这类患者手术治疗的选择。然而,应警告肥胖患者,其肥胖程度可能与手术难度增加有关,表现为手术时间延长和术中并发症增多的趋势。