Bautista Ramon Edmundo D, Godwin Steven, Caro David
Department of Neurology, University of Florida Health Sciences Center, Jacksonville, Florida 32209, USA.
J Clin Neurophysiol. 2007 Feb;24(1):16-21. doi: 10.1097/WNP.0b013e318030e8cb.
Patients frequently present to the emergency room (ER) with mental status changes without obvious cause. The EEG is underused in this population. The authors investigated whether an abbreviated EEG (AbEEG) can be incorporated in the early evaluation of these patients to provide useful information. A 5-minute AbEEG was performed using a preformed electrode placement system on 25 patients who presented to the ER with mental status changes of unknown cause. AbEEG findings were categorized as normal, showing diffuse abnormalities, focal abnormalities, electrographic seizures, or uninterpretable. Using retrospective chart review, the authors determined if the cause of mental status change was a diffuse encephalopathy or a nonneurologic event (DENNE), a focal brain abnormality, nonconvulsive status epilepticus (NCSE), psychogenic, or unknown, and if particular AbEEG findings were associated with specific causes of altered sensorium. The AbEEG identified NCSE in two patients who presented with new-onset seizures. The presence of diffuse slowing on the AbEEG was highly suggestive of mental status changes due to DENNE. AbEEGs can be successfully incorporated in the early evaluation of patients who present to the ER with mental status changes of unknown cause and provide useful information in this setting.
患者常常在没有明显病因的情况下出现精神状态改变并前往急诊室(ER)就诊。脑电图(EEG)在这类人群中的应用不足。作者研究了是否可以将简化脑电图(AbEEG)纳入对这些患者的早期评估中,以提供有用信息。使用预制电极放置系统对25名因不明原因出现精神状态改变而前往急诊室的患者进行了5分钟的AbEEG检查。AbEEG结果分为正常、显示弥漫性异常、局灶性异常、脑电图癫痫发作或无法解读。通过回顾性病历审查,作者确定精神状态改变的原因是弥漫性脑病或非神经系统事件(DENNE)、局灶性脑异常、非惊厥性癫痫持续状态(NCSE)、心因性还是不明原因,以及特定的AbEEG结果是否与意识改变的特定原因相关。AbEEG在两名新发癫痫发作的患者中识别出了NCSE。AbEEG上弥漫性减慢的出现强烈提示因DENNE导致的精神状态改变。AbEEG可以成功纳入对因不明原因出现精神状态改变而前往急诊室的患者的早期评估中,并在此情况下提供有用信息。