Szabó B, Szöllösi G J, Gönci B, Jurányi Zs, Selmeczi D, Vicsek Tamás
Department of Biological Physics, Eötvös University, Pázmány P. stny. 1A, H-1117 Budapest, Hungary.
Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Dec;74(6 Pt 1):061908. doi: 10.1103/PhysRevE.74.061908. Epub 2006 Dec 22.
We have recorded the swarming-like collective migration of a large number of keratocytes (tissue cells obtained from the scales of goldfish) using long-term videomicroscopy. By increasing the overall density of the migrating cells, we have been able to demonstrate experimentally a kinetic phase transition from a disordered into an ordered state. Near the critical density a complex picture emerges with interacting clusters of cells moving in groups. Motivated by these experiments we have constructed a flocking model that exhibits a continuous transition to the ordered phase, while assuming only short-range interactions and no explicit information about the knowledge of the directions of motion of neighbors. Placing cells in microfabricated arenas we found spectacular whirling behavior which we could also reproduce in simulations.
我们使用长期视频显微镜记录了大量角膜细胞（从金鱼鳞片获得的组织细胞）的类群体集体迁移。通过增加迁移细胞的整体密度，我们能够通过实验证明从无序状态到有序状态的动力学相变。在临界密度附近，出现了一幅复杂的图景，相互作用的细胞簇成群移动。受这些实验的启发，我们构建了一个群聚模型，该模型展示了向有序相的连续转变，同时仅假设存在短程相互作用，且没有关于邻居运动方向的明确信息。将细胞放置在微制造的区域中，我们发现了壮观的旋转行为，这种行为我们也能在模拟中重现。
