双侧苍白球深部脑刺激治疗原发性颈部肌张力障碍的长期疗效

Long-term outcome of bilateral pallidal deep brain stimulation for primary cervical dystonia.

作者信息

Hung S W, Hamani C, Lozano A M, Poon Y-Y W, Piboolnurak P, Miyasaki J M, Lang A E, Dostrovsky J O, Hutchison W D, Moro E

机构信息

Movement Disorders Centre, Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada M5T 2S8.

出版信息

Neurology. 2007 Feb 6;68(6):457-9. doi: 10.1212/01.wnl.0000252932.71306.89.

DOI:10.1212/01.wnl.0000252932.71306.89

PMID:17283323

Abstract

Ten patients with severe cervical dystonia (CD) unresponsive to medical treatment underwent bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) and were followed for 31.9 +/- 20.9 months. At last follow-up, the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) severity score improved by 54.8%, the TWSTRS disability score improved by 59.1%, and the TWSTRS pain score improved by 50.4%. Bilateral GPi DBS is an effective long-term therapy in patients with CD.

摘要

10例药物治疗无效的重度颈部肌张力障碍（CD）患者接受了双侧内侧苍白球（GPi）深部脑刺激（DBS）治疗，并随访了31.9±20.9个月。在最后一次随访时，多伦多西部痉挛性斜颈评定量表（TWSTRS）严重程度评分改善了54.8%，TWSTRS残疾评分改善了59.1%，TWSTRS疼痛评分改善了50.4%。双侧GPi DBS是治疗CD患者的一种有效的长期疗法。