Busquets Joan Carles Vilanova, Batlle Josep Comet, Obregón Joaquim Barceló, Ortega Miguel Villalón, Morell Nus Ruscadella
Departamento de Resonancia Magnética, Clínica Girona, Lorenzana, 36, 17002 Girona, España.
Arch Esp Urol. 2006 Dec;59(10):1001-10.
The management of prostate cancer represents a real clinical problem for its unknown natural history, and unpredictable outcome and prognosis. The stage is the most important prognostic variable of any tumor. The use of nomograms, such as Partin's tables, supplies important information for the evaluation of the local stage. Nevertheless, these methods have low reliability because they do not use anatomical information of the gland. The development of MRI techniques incorporating high-resolution anatomical evaluation of the prostate in conjunction with metabolic information (MRI spectroscopy) offer the imaging technique of choice for the staging of prostate cancer in selected patients candidates to curative surgery. Prostate MRI offers the most reliable evaluation of local and regional staging. Anyway, many studies have described a wide variability in the reliability of prostate cancer staging by MRI, indicating that MRI is not a perfect imaging test because it cannot detect microscopic involvement. The objective of this article is to evaluate the current role of prostatic MRI for prostate cancer staging, evaluating its advantages, limitations and future expectations.
前列腺癌的管理因其未知的自然病史、不可预测的结果和预后而成为一个实际的临床问题。分期是任何肿瘤最重要的预后变量。使用诺模图,如帕廷表格,可为局部分期的评估提供重要信息。然而,这些方法可靠性较低,因为它们未利用腺体的解剖信息。结合前列腺高分辨率解剖评估与代谢信息的MRI技术(MRI光谱学)的发展,为适合根治性手术的特定患者的前列腺癌分期提供了首选的成像技术。前列腺MRI能对局部和区域分期进行最可靠的评估。无论如何,许多研究都描述了MRI对前列腺癌分期可靠性的广泛差异,这表明MRI并非完美的成像检查,因为它无法检测到微观侵犯。本文的目的是评估前列腺MRI在前列腺癌分期中的当前作用,评估其优势、局限性和未来期望。