Fatal genital verrucous carcinoma.

A rare, fatal case of verrucous carcinoma on the labia majora of a 65-year-old woman is presented. Histopathologically, the neoplasm was repeatedly diagnosed as a verruca over the course of many years. A diagnosis of verrucous carcinoma was rendered only after the documentation of lymph node metastasis. Although most cases of verrucous carcinoma have a favorable prognosis, this case illustrates that verrucous carcinoma can metastasize even when the neoplasm is superficially situated and the histopathologic findings are subtle.