Grover Michael L, Bracamonte Jesse D, Kanodia Anup K, Bryan Michael J, Donahue Sean P, Warner Anne-Marie, Edwards Frederick D, Weaver Amy L
Department of Family Medicine, Mayo Clinic College of Medicine, 13737 N 92nd St, Scottsdale, AZ 85260, USA.
Mayo Clin Proc. 2007 Feb;82(2):181-5. doi: 10.4065/82.2.181.
To assess adherence to evidence-based guidelines for the diagnosis and management of uncomplicated urinary tract infection (UTI) in a family medicine residency clinic setting.
We retrospectively reviewed the medical records of female patients seen in 2005 at the Mayo Clinic Family Medicine Center in Scottsdale, Ariz, who were identified by International Classification of Diseases, Ninth Revision code 599.0 (UTI). We assessed documentation rates, use of diagnostic studies, and antibiotic treatments. Antibiotic sensitivity patterns from outpatient urine culture and sensitivity analyses were determined.
Of 228 patients, 68 (30%) had uncomplicated UTI. Our physicians recorded essential history and examination findings for most patients. Documentation of the risk of sexually transmitted disease differed between residents and attending physicians and was affected by patient age. Urine dipstick and urine culture and sensitivity analyses were ordered in 57 (84%) and 52 (76%) patients, respectively. Eighty percent of patients with positive results on urine dipstick analyses also had urine culture and sensitivity analyses. Sulfamethoxazole-trimethoprim (SMX-TMP) was used as initial therapy in 26 patients (38%). Sixty-one percent of SMX-TMP and ciprofloxacin prescriptions were appropriately provided for 3 days. Escherichia coil was sensitive to SMX-TMP in 33 (94%) of 35 cultures. Treatment was not changed in any patient with an uncomplicated UTI because of results of urine culture and sensitivity analyses. Antibiotic sensitivity patterns for outpatients were significantly different from those for inpatients.
Only 30% of our patients had uncomplicated UTI, making their management within clinical guidelines appropriate. However, of those patients with uncomplicated UTI, less than 25% received empirical treatment as suggested. Urine culture and sensitivity analyses were performed frequently, even in patients who already had positive results on a urine dip-stick analysis. Although SMX-TMP is effective, it is underused. On the basis of these findings, we hope to provide interventions to increase SMX-TMP prescription, decrease use of urine culture and sensitivity analyses, and increase the frequency of 3-day antibiotic treatments at our institution.
评估在家庭医学住院医师诊所环境中,对单纯性尿路感染(UTI)诊断和管理的循证指南的遵循情况。
我们回顾性分析了2005年在亚利桑那州斯科茨代尔市梅奥诊所家庭医学中心就诊的女性患者的病历,这些患者通过国际疾病分类第九版编码599.0(UTI)得以确定。我们评估了记录率、诊断性检查的使用情况以及抗生素治疗情况。确定了门诊尿培养的抗生素敏感性模式并进行敏感性分析。
在228例患者中,68例(30%)患有单纯性UTI。我们的医生为大多数患者记录了基本病史和检查结果。住院医师和主治医师在记录性传播疾病风险方面存在差异,且受患者年龄影响。分别有57例(84%)和52例(76%)患者接受了尿试纸检查以及尿培养和敏感性分析。尿试纸分析结果呈阳性的患者中,80%也进行了尿培养和敏感性分析。26例患者(38%)使用磺胺甲恶唑 - 甲氧苄啶(SMX - TMP)作为初始治疗。61%的SMX - TMP和环丙沙星处方的用药时长为3天,这是恰当的。在35份培养样本中,33份(94%)的大肠埃希菌对SMX - TMP敏感。由于尿培养和敏感性分析结果,没有任何一位单纯性UTI患者的治疗方案发生改变。门诊患者的抗生素敏感性模式与住院患者显著不同。
我们的患者中只有30%患有单纯性UTI,因此按照临床指南对其进行管理是合适的。然而,在那些患有单纯性UTI的患者中,接受建议的经验性治疗的患者不到25%。即使在尿试纸分析结果已呈阳性的患者中,尿培养和敏感性分析仍经常进行。虽然SMX - TMP有效,但使用不足。基于这些发现,我们希望在本机构提供干预措施,以增加SMX - TMP的处方量,减少尿培养和敏感性分析的使用,并提高3天抗生素治疗的频率。