Palmer David, Lallu Sharda, Matheson Philip, Bethwaite Peter, Tompson Keneth
Department of Cytology, Wellington Hospital and School of Medicine, Capital and Coast District Health Board, Wellington, New Zealand.
Diagn Cytopathol. 2007 Mar;35(3):179-82. doi: 10.1002/dc.20603.
A case of a 44-yr-old Maori female presenting with chronic renal failure due to karyomegalic interstitial nephritis is reported. To our knowledge, this is the first instance this disorder has been reported in a New Zealand Maori. Karyomegalic interstitial nephritis is a rare cause of progressive renal failure, which may be familial, and is frequently associated with a history of recurrent respiratory infections. The urine in this case contained large, pleomorphic cells, mimicking carcinoma. The case therefore illustrates a rare cause of chronic renal failure, and presents an important diagnostic pitfall in the practice of urine cytopathology.
报告了一例44岁毛利族女性因核肿大性间质性肾炎导致慢性肾衰竭的病例。据我们所知，这是该疾病首次在新西兰毛利族中被报道。核肿大性间质性肾炎是进行性肾衰竭的罕见病因，可能具有家族性，且常与反复呼吸道感染史相关。该病例的尿液中含有大的、多形性细胞，类似癌细胞。因此，该病例说明了慢性肾衰竭的一种罕见病因，并在尿液细胞病理学实践中呈现出一个重要的诊断陷阱。
