Murray Anthony David Neil, Orpen Jane, Calcutt Carolyn
Division of Ophthalmology, Faculty of Health Sciences, University of Cape Town and Groote Schuur Hospital, Cape, South Africa.
J AAPOS. 2007 Apr;11(2):125-30. doi: 10.1016/j.jaapos.2006.10.016. Epub 2007 Feb 15.
Most studies of infantile esotropia concern patients diagnosed in infancy and treated throughout childhood. This prospective study addresses changes in the functional binocular status of older children and adults with previously untreated infantile esotropia, following late surgical realignment.
Seventeen patients aged 8 years or more with a history of untreated esotropia occurring within the first 6 months of life were included in this study. All had monocular optokinetic asymmetry, a visual acuity of 20/30 or better in the worse eye, and binocular function assesment preoperatively and postoperatively. All were surgically aligned within 8(Delta) of orthotropia. None had neurologic disease.
Preoperatively, all 17 patients demonstrated a monocular response to Bagolini lenses, while postoperatively 15 (88%) of the 17 demonstrated binocular function with Bagolini lenses (in that they could constantly perceive the major part of both arms of the X generated by the Bagolini lenses) and 13/17 (76%) demonstrated an increase in the binocular field. All 17 had no sensory fusion, either preoperatively or postoperatively, when tested with the Worth 4-Dot test or synoptophore, and no stereopsis with the Titmus stereo test.
Older children and adults with previously untreated infantile esotropia derive some functional benefits following late surgical realignment. The degree of binocular function may be lower than that achieved in patients aligned before 24 months of age.
大多数关于婴儿型内斜视的研究关注于在婴儿期被诊断并在整个儿童期接受治疗的患者。这项前瞻性研究探讨了患有未经治疗的婴儿型内斜视的大龄儿童和成人在晚期手术矫正后其功能性双眼状态的变化。
本研究纳入了17例年龄在8岁及以上、有出生后6个月内未经治疗的内斜视病史的患者。所有患者均有单眼视动性不对称,较差眼的视力为20/30或更好,并在术前和术后进行了双眼功能评估。所有患者均通过手术矫正至正位相差8(棱镜度)以内。无一例患有神经系统疾病。
术前,所有17例患者对巴戈里尼氏透镜均表现出单眼反应,而术后,17例中有15例(88%)对巴戈里尼氏透镜表现出双眼功能(即他们能够持续感知巴戈里尼氏透镜产生的X形的两条主要臂),13/17例(76%)双眼视野有所增加。在使用沃思四点试验或同视机测试时,所有17例患者术前和术后均无感觉融合,使用蒂特莫斯立体视觉测试时均无立体视。
患有未经治疗的婴儿型内斜视的大龄儿童和成人在晚期手术矫正后可获得一些功能上的益处。其双眼功能程度可能低于24个月前接受矫正的患者。