短暂性新生儿甲状腺功能减退症与新生儿及其母亲血清抗甲状腺球蛋白抗体水平升高有关。
Transient neonatal hypothyroidism is associated with elevated serum anti-thyroglobulin antibody levels in newborns and their mothers.
作者信息
Ordookhani Arash, Mirmiran Parvin, Walfish Paul G, Azizi Fereidoun
机构信息
Endocrine Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
J Pediatr. 2007 Mar;150(3):315-7, 317.e2. doi: 10.1016/j.jpeds.2006.11.034.
Transient congenital hypothyroidism (TCH) was detected in 6 of 35,067 newborns (1:5845 births) screened in Iran. Antithyroglobulin antibodies positivity was present in 4 of 6 (66.7%) of those with TCH and in 6 of 106 (5.7%) of those with "transient hyperthyrotropinemia and normal" diagnoses (P = .0005), but positivity was similar in newborns with transient hyperthyrotropinemia versus normal neonates (P = .397).
在伊朗接受筛查的35067名新生儿中，有6例（1:5845出生）被检测出患有暂时性先天性甲状腺功能减退症（TCH）。6例TCH患者中有4例（66.7%）抗甲状腺球蛋白抗体呈阳性，而在106例诊断为“暂时性促甲状腺素血症且正常”的患者中有6例（5.7%）呈阳性（P = .0005），但暂时性促甲状腺素血症新生儿与正常新生儿的阳性率相似（P = .397）。
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