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旋毛虫在大鼠体内的发育

[In vivo development of Trichinella spiralis in rats].

作者信息

Inceboz Tonay, Ozkoç Soykan, Akisü Ciler

机构信息

Dokuz Eylül Universitesi Tip Fakültesi Parazitoloji Anabilim Dali, Inciralti, Izmir, Turkey.

出版信息

Turkiye Parazitol Derg. 2006;30(4):289-92.

Abstract

The causative agent is Trichinella spiralis which lives in the intestines in adult form or in skeletal muscles in larval form. After ingestion of raw or undercooked infected meat that contains larvae of trichinella, these larvae enter the blood and the lymphatic circulation. They usually settle in the skeletal muscles and develop further. This study was conducted in the Department of Parasitology of the Dokuz Eylul University, School of Medicine. The aim of this experimental study was to develop Trichinella spiralis in vivo experimentally using Wistar albino rats. It was also found that Trichinella spiralis can be experimentally developed in the Rattus norvegicus species of rodents, and it is possible to use the obtained Trichinella spiralis larva's for numerous purposes, in particular for supplying the antigens required for serological diagnosis of the disease. In addition, we investigated the range of the the skeletal muscles in which the causative agent, Trichinella spiralis, lives in larval form.

摘要

病原体是旋毛虫,其成虫生活在肠道中,幼虫生活在骨骼肌中。摄入含有旋毛虫幼虫的生肉或未煮熟的受感染肉类后,这些幼虫进入血液和淋巴循环。它们通常定居在骨骼肌中并进一步发育。本研究在多库兹艾吕尔大学医学院寄生虫学系进行。这项实验研究的目的是使用Wistar白化大鼠在体内实验性培养旋毛虫。还发现旋毛虫可以在挪威大鼠种的啮齿动物中进行实验性培养,并且可以将获得的旋毛虫幼虫用于多种目的,特别是用于提供该疾病血清学诊断所需的抗原。此外,我们研究了病原体旋毛虫以幼虫形式生活的骨骼肌范围。

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