Wolf Robert Christian, Spiess Jochen, Vasic Nenad, Huber Roman
Department of Neurology, University of Ulm, Ulm, Germany.
Eur Neurol. 2007;57(4):227-31. doi: 10.1159/000100016. Epub 2007 Feb 20.
We report the case of a previously healthy 47-year-old woman suffering an acute embolic stroke in the left middle cerebral artery distribution. A filiform structure along the line of the aortic valve was first identified by transesophageal echocardiography, leading to the diagnosis of a valvular strand. These masses are thought to represent giant Lambl's excrescences, although differential diagnoses include several benign cardiac tumors, e.g. papillary fibroelastoma. Valvular strands have previously been associated with embolic events including stroke, although exact pathogenetic mechanisms and further patient management have not yet been fully established. This case report additionally provides a short overview of the currently existing literature. As a conclusion, standard recommendations for patient management and treatment cannot be derived from currently available evidence.
我们报告了一例既往健康的47岁女性,其左侧大脑中动脉分布区发生急性栓塞性中风。经食管超声心动图首次发现沿主动脉瓣走行的丝状结构,从而诊断为瓣膜条索。这些肿物被认为是巨大的兰布尔赘生物,尽管鉴别诊断包括几种良性心脏肿瘤,如乳头状纤维弹性瘤。瓣膜条索此前已与包括中风在内的栓塞事件相关联,尽管确切的发病机制和进一步的患者管理尚未完全明确。本病例报告还简要概述了当前的现有文献。结论是,目前无法从现有证据中得出患者管理和治疗的标准建议。