Inoue Yoshito, Ueda Toshihiko, Taguchi Shinichi, Kashima Ichiro, Koizumi Kiyoshi, Takahashi Ryuichi, Kiso Issei
Department of Cardiovascular Surgery, Saiseikai Utsunomiya Hospital, 911-1 Takebayashi, Utsunomiya, Tochigi 321-0974, Japan.
Eur J Cardiothorac Surg. 2007 Jun;31(6):976-9; discussion 979-81. doi: 10.1016/j.ejcts.2007.01.048. Epub 2007 Feb 22.
Antegrade perfusion for type A acute aortic dissection prevents malperfusion and retrograde cerebral embolism during cardiopulmonary bypass. Prompt establishment of antegrade perfusion via ascending aorta may improve the surgical results of type A dissections, especially in the situations of hemodynamic instability. Thus, we evaluated the efficacy of use of the dissected ascending aorta as an alternative arterial inflow.
Between 2002 and 2006, 32 patients underwent prosthetic graft replacement of the ascending aorta or hemiarch for acute type A aortic dissection. The ascending aorta was routinely cannulated, in addition to the femoral artery, with a heparin-coating flexible cannula for arterial inflow, using Seldinger technique, and by epiaortic ultrasonographic guidance (n=6). Antegrade systemic perfusion via ascending aorta was performed.
Ascending aorta cannulation was safely performed in all cases. There was no malperfusion or thromboembolism due to ascending aorta cannulation. Cardiopulmonary bypass was established within 30 min after skin incision. There was one in-hospital death due to duodenal bleeding (1/32=3.1%), two cases of cerebral infarction (2/32=6.3%), and one case of pulmonary embolism. Twenty-nine patients (29/32=90.6%) were discharged in New York Heart Association class I and have been followed up uneventfully for a mean of 17 months.
Antegrade perfusion via the ascending aorta was successfully performed with low mortality and morbidity. With ultrasound-guided Seldinger technique, ascending aorta cannulation has a potential to be a simple and safe option that enables rapid establishment of antegrade systemic perfusion in patients with acute type A aortic dissection.
A型急性主动脉夹层的顺行灌注可预防体外循环期间的灌注不良和逆行性脑栓塞。通过升主动脉迅速建立顺行灌注可能会改善A型夹层的手术效果,尤其是在血流动力学不稳定的情况下。因此,我们评估了使用夹层升主动脉作为替代动脉流入道的有效性。
2002年至2006年期间,32例患者因急性A型主动脉夹层接受了升主动脉或半弓的人工血管置换术。除股动脉外,常规使用肝素涂层的可弯曲插管,采用Seldinger技术并在主动脉超声引导下(n = 6),经升主动脉插管用于动脉流入,进行顺行性全身灌注。
所有病例均安全完成升主动脉插管。未发生因升主动脉插管导致的灌注不良或血栓栓塞。皮肤切开后30分钟内建立了体外循环。有1例因十二指肠出血死亡(1/32 = 3.1%),2例脑梗死(2/32 = 6.3%),1例肺栓塞。29例患者(29/32 = 90.6%)以纽约心脏协会I级出院,平均随访17个月,情况良好。
经升主动脉的顺行灌注成功实施,死亡率和发病率较低。采用超声引导下的Seldinger技术,升主动脉插管有可能成为一种简单安全的选择,能够在急性A型主动脉夹层患者中迅速建立顺行性全身灌注。