一项针对老年患者股骨颈囊内移位骨折,比较双极半髋关节置换术与全髋关节置换术的随机对照试验。
A randomised controlled trial comparing bipolar hemiarthroplasty with total hip replacement for displaced intracapsular fractures of the femoral neck in elderly patients.
作者信息
Blomfeldt R, Törnkvist H, Eriksson K, Söderqvist A, Ponzer S, Tidermark J
机构信息
Department of Orthopedics, Karolinska Institutet, Stockholm Söder Hospital, Stockholm S-11883, Sweden.
出版信息
J Bone Joint Surg Br. 2007 Feb;89(2):160-5. doi: 10.1302/0301-620X.89B2.18576.
The best treatment for the active and lucid elderly patient with a displaced intracapsular fracture of the femoral neck is still controversial. Randomised controlled trials have shown that a primary total hip replacement is superior to internal fixation as regards the need for secondary surgery, hip function and health-related quality of life. Despite good results achieved with total hip replacement in this group, most orthopaedic surgeons still advocate hemiarthroplasty for this injury. We studied 120 patients with a mean age of 81 years (70 to 90) with an acute displaced intracapsular fracture of the femoral neck. They were randomly allocated to be treated with either a bipolar hemiarthroplasty or total hip replacement. Outcome measurements included peri-operative data, general and hip-specific complications, hip function and health-related quality of life. The patients were reviewed at four and 12 months. The duration of surgery was longer in the total hip replacement group (102 minutes (70 to 151)) versus 78 minutes (43 to 131) (p<0.001), and the intra-operative blood loss was increased 460 ml (100 to 1100) versus 320 ml (50 to 850) (p<0.001), but there were no differences between the groups regarding any complications or mortality. There were no dislocations in either group. Hip function measured by the Harris hip score was significantly better in the total hip replacement group at both follow-up periods (p=0.011 and p<0.001, respectively). The health-related quality of life measure was in favour of the total hip replacement group but did not reach statistical significance (p=0.818 at four months and p=0.636 at 12 months). These results indicate that a total hip replacement provides better function than a bipolar hemiarthroplasty as soon as one year post-operatively, without increasing the complication rate. We recommend total hip replacement as the primary treatment for this group of patients.
对于活跃且神志清醒的老年股骨颈囊内移位骨折患者,最佳治疗方法仍存在争议。随机对照试验表明,在二次手术需求、髋关节功能及与健康相关的生活质量方面,初次全髋关节置换术优于内固定术。尽管全髋关节置换术在该组患者中取得了良好效果,但大多数骨科医生仍主张对此类损伤采用半髋关节置换术。我们研究了120例平均年龄81岁(70至90岁)的急性股骨颈囊内移位骨折患者。他们被随机分配接受双极半髋关节置换术或全髋关节置换术治疗。结果测量包括围手术期数据、一般及髋关节特异性并发症、髋关节功能及与健康相关的生活质量。在4个月和12个月时对患者进行复查。全髋关节置换组的手术时间更长(102分钟(70至151分钟)),而半髋关节置换组为78分钟(43至131分钟)(p<0.001),术中失血量增加(全髋关节置换组为460毫升(100至1100毫升),半髋关节置换组为320毫升(50至850毫升))(p<0.001),但两组在任何并发症或死亡率方面无差异。两组均无脱位情况。在两个随访期,通过Harris髋关节评分测量的髋关节功能在全髋关节置换组均显著更好(分别为p=0.011和p<0.001)。与健康相关的生活质量测量结果倾向于全髋关节置换组,但未达到统计学显著性(4个月时p=0.818,12个月时p=0.636)。这些结果表明,术后一年,全髋关节置换术比双极半髋关节置换术提供更好的功能,且不增加并发症发生率。我们建议将全髋关节置换术作为该组患者的主要治疗方法。