对于即将接受冠状动脉搭桥手术的患者，术后勃起功能的最佳预测指标是什么？

What is the best predictor of postoperative erectile function in patients who will undergo coronary artery bypass surgery?

作者信息

Hizli Fatih, Işler Burak, Güneş Zeki, Ozatik M Ali, Berkmen Ferhat

机构信息

Department of Urology, Oncology Education and Research Hospital, Demetevler, Ankara, 06530, Turkey.

出版信息

Int Urol Nephrol. 2007;39(3):909-12. doi: 10.1007/s11255-006-9118-1. Epub 2007 Mar 2.

DOI:10.1007/s11255-006-9118-1

PMID:17333526

Abstract

PURPOSE

The aim of this prospective study was to evaluate the impact of extracorporeal circulation and cross clamping period on erectile function in patients undergoing coronary artery bypass surgery (CABS).

MATERIALS AND METHODS

A total of 50 patients undergoing CABS were evaluated in this prospective study. Before and 6-12 months after the CABS, patients were interviewed for erectile dysfunction (ED) using the International Index of Erectile Function (IIEF). Scoring the IIEF domain of erectile function allowed the classification of each patient as having no (26-30), mild (17-25), moderate (11-16) or severe (0-10) ED. Patients with normal, mild and moderate ED score were designated as group A, B and C, respectively. Patients were classified in 2 groups to evaluate the impact of extracorporeal circulation and cross clamping period on erectile function in patients undergoing CABS. Patients who had no change in ED score in group A and patients who had recovery in group B were included in group1. Patients who had impaired ED score in group A and group B were included in group 2. All patients were also interviewed for sociodemographic and relevant medical history. Sociodemographic data were age, job, marital status, alcohol, narcotic and smoking habit. Medical risk factors were diabetes, hypertension and psychiatric disorders.

RESULTS

The mean age of patients included in the study were 46,6 (range 31-55). After the operation, 3 (7.5%) of 41 patients in group A had moderate, 1 (2.5%) had mild and 37 (90%) had no change in ED score. In group B, 2 (28%) of 7 patients had moderate, 4 (57%) had recovery in ED score, 1 had no change in ED score. There were only 2 patients in group C and 1 had severe, the other one had mild ED after the operation. The mean operation period was 234.8 m inutes in group 1 and 280 min in group 2. Cross clamping period and extracorporeal circulation of patients in group 1 and 2 were 33.2, 41.6 min and 54.7, 64.6 min, respectively. The groups were not statistically different with regard to mean operation, cross clamping and extracorporeal circulation period.

CONCLUSION

Preoperative erectile function seems to be the best predictor of postoperative erectile function in patients who will undergo CABS.

摘要

目的

本前瞻性研究的目的是评估体外循环和交叉钳夹期对接受冠状动脉搭桥手术（CABS）患者勃起功能的影响。

材料与方法

本前瞻性研究共评估了50例接受CABS的患者。在CABS术前及术后6 - 12个月，使用国际勃起功能指数（IIEF）对患者进行勃起功能障碍（ED）访谈。对IIEF勃起功能领域进行评分，可将每位患者分类为无（26 - 30分）、轻度（17 - 25分）、中度（11 - 16分）或重度（0 - 10分）ED。ED评分正常、轻度和中度的患者分别被指定为A组、B组和C组。将患者分为2组，以评估体外循环和交叉钳夹期对接受CABS患者勃起功能的影响。A组中ED评分无变化的患者和B组中勃起功能恢复的患者被纳入第1组。A组和B组中ED评分受损的患者被纳入第2组。所有患者还接受了社会人口统计学和相关病史的访谈。社会人口统计学数据包括年龄、工作、婚姻状况、饮酒、使用麻醉品和吸烟习惯。医学风险因素包括糖尿病、高血压和精神疾病。

结果

纳入研究的患者平均年龄为46.6岁（范围31 - 55岁）。术后，A组41例患者中有3例（7.5%）为中度ED，1例（2.5%）为轻度ED，37例（90%）ED评分无变化。在B组，7例患者中有2例（28%）为中度ED，4例（57%）勃起功能恢复，1例ED评分无变化。C组仅有2例患者，术后1例为重度ED，另1例为轻度ED。第1组的平均手术时间为234.8分钟，第2组为280分钟。第1组和第2组患者的交叉钳夹期和体外循环时间分别为33.2、41.6分钟和54.7、64.6分钟。两组在平均手术、交叉钳夹和体外循环时间方面无统计学差异。