Hedman M, Brandstätter A, Pimenoff V, Sistonen P, Palo J U, Parson W, Sajantila A
Laboratory of Forensic Biology, Department of Forensic Medicine, University of Helsinki, Finland.
Forensic Sci Int. 2007 Oct 25;172(2-3):171-8. doi: 10.1016/j.forsciint.2006.09.012. Epub 2007 Mar 2.
We have analyzed the two hypervariable regions HVS-I and HVS-II of 200 Finnish male individuals for forensic purposes. The distribution of the haplotypes within Finland was determined by the geographical knowledge of the donors' maternal ancestors. In our population sample, we identified 135 different mtDNA haplotypes. Different mtDNA sequences were further divided to haplogroups using the EMPOP software. The most common haplogroups were H (40.0%) and U (27.5%). Subgroup U5b, which contains earlier described "Saami motif", consisted majority (65.5%) of the sample in the U haplogroup. Analysis of the mtDNA sequence hypervariable regions I and II showed that the mtDNA diversity within the Finnish population sample was comparable to other European populations and uniformly distributed. This is contrary to the Y-STR "minimal haplotype" diversity, which in Finland is lower than in any of the other European populations studied so far.
为了法医鉴定目的，我们分析了200名芬兰男性个体的两个高变区HVS-I和HVS-II。芬兰境内单倍型的分布是由捐献者母系祖先的地理信息确定的。在我们的人群样本中，我们鉴定出135种不同的线粒体DNA单倍型。使用EMPOP软件将不同的线粒体DNA序列进一步划分为单倍群。最常见的单倍群是H（40.0%）和U（27.5%）。包含先前描述的“萨米基序”的亚群U5b，在U单倍群样本中占多数（65.5%）。对线粒体DNA序列高变区I和II的分析表明，芬兰人群样本中的线粒体DNA多样性与其他欧洲人群相当，且分布均匀。这与Y-STR“最小单倍型”多样性相反，在芬兰，Y-STR“最小单倍型”多样性低于迄今为止研究的任何其他欧洲人群。
