Konstantinović Ljubica, Devecerski Gordana, Petronić Ivana, Jović Stevan, Cutović Milisav, Cirović Dragana
Medicinski fakultet Beograd Klinika za rehabilitaciju "Dr Miroslav Zotović.
Med Pregl. 2006;59 Suppl 1:35-9.
Low back pain is one of the most frequent health problems. The aim of the study was to investigate clinical effects of complex rehabilitation programs on quality of life of patients with subacute lumbar pain, and also to investigate the relationship between quality of life and the intensity of pain and local functional status of the lumbar spine.
The prospective study included 60 patients suffering from subacute low back pain with radiculopathy caused by lumbar disc syndrome, without any previous treatment, and who did not need surgery. In a single blind trial patients were divided into two groups. The first group (A group, n=30) was treated by low level laser therapy (wavelength 904 nm, frequency 4000 Hz, at dose 2J per point); the whole dose of 12J, then with TENS (frequency 80 Hz, 30 minutes, pulse duration 200 micros), with exercise, and simultaneously with conventional therapy with NSAIDs which inhibit COX-2 (meloxicam, 15 mg per day). Patients were treated 5 times a week, a total of 15 treatments. The second group (B group, n =30), was treated only by meloxicam (15 mg per day). The subjects were evaluated before the first treatment and three days after the last treatment (21st to 24th day). Data were analyzed using Student's t test and with analytic statistical methods.
The mean Oswestry scores before and after therapy for group A have reduced from 25+/-2 to 16+/-3, with statistical significance (t= 8.84 p<0.001) and in group B from 24+/-2.5 to 22+/-2.5 (t=2.56 p<0.05). Statistical analysis has shown an increase of mean values for the 12-item health survey (SF-12) from 22.33+/-4.66 to 36.33+/-3.66 (t=9.12 p<0.001), in group A and from 23.66+/-3.66 to 30.33+/-4.66 (t=3.15 p <0.001) in group B. Mean values of intensity of pain in group A have been reduced from 82+/-6.50 to 46+/-5.50, (t=7.85, p<0.001) and from 80+/-5.50 to 62+/-6.50 in group B (t=5.65; p<0.001). No significant changes have been recorded in Schober measurement. The intensity of pain was in positive correlation with Oswestry score (Ft=7.84; p<0.001) in group A and also in group B (Ft=5.25: p<0.05), as for the 12-item health survey (SF-12) (Ft=8.34: p<0.001) in group A and in group B (Ft=5.98; p<0.05). Two measurements of quality of life have shown close relationship (Ft=5.45; p<0.05) in group A and group B (Ft=6.45: p<0.05).
Results of this study showed that better results were achieved in group treated with complex rehabilitation methods in comparison with patients treated only with anti-inflammatory drugs. Also, the 12-item health survey (SF-12) has shown positive correlation with intensity of pain reduction and with Oswestry disability score and so it is valid for measuring the effectiveness of therapeutic modalities in subacute lumbar pain.
腰痛是最常见的健康问题之一。本研究的目的是调查综合康复方案对亚急性腰痛患者生活质量的临床效果,并研究生活质量与疼痛强度以及腰椎局部功能状态之间的关系。
这项前瞻性研究纳入了60例患有亚急性腰痛并伴有腰椎间盘综合征引起的神经根病的患者,这些患者之前未接受过任何治疗且无需手术。在单盲试验中,患者被分为两组。第一组(A组,n = 30)接受低强度激光治疗(波长904 nm,频率4000 Hz,每点剂量2J);总剂量为12J,然后进行经皮电刺激神经疗法(频率80 Hz,30分钟,脉冲持续时间200微秒),同时进行运动,并与抑制COX - 2的非甾体抗炎药(美洛昔康,每天15 mg)的常规治疗同时进行。患者每周接受5次治疗,共15次。第二组(B组,n = 30)仅接受美洛昔康治疗(每天15 mg)。在第一次治疗前和最后一次治疗后三天(第21至24天)对受试者进行评估。数据采用学生t检验和分析统计方法进行分析。
A组治疗前后的平均Oswestry评分从25±2降至16±3,具有统计学意义(t = 8.84,p < 0.001),B组从24±2.5降至22±2.5(t = 2.56,p < 0.05)。统计分析表明,A组12项健康调查(SF - 12)的平均值从22.33±4.66增加到36.33±3.66(t = 9.12,p < 0.001),B组从23.66±3.66增加到30.33±4.66(t = 3.15,p < 0.001)。A组疼痛强度的平均值从82±6.50降至46±5.50(t = 7.85,p < 0.001),B组从80±5.50降至62±6.50(t = 5.65;p < 0.001)。Schober测量未记录到显著变化。A组和B组中,疼痛强度与Oswestry评分呈正相关(A组:Ft = 7.84;p < 0.001;B组:Ft = 5.25:p < 0.05),与12项健康调查(SF - 12)也呈正相关(A组:Ft = 8.34:p < 0.001;B组:Ft = 5.98;p < 0.05)。两组的两次生活质量测量结果显示出密切关系(A组:Ft = 5.45;p < 0.05;B组:Ft = 6.45:p < 0.05)。
本研究结果表明,与仅接受抗炎药物治疗的患者相比,采用综合康复方法治疗的组取得了更好的效果。此外,12项健康调查(SF - 12)与疼痛减轻强度以及Oswestry残疾评分呈正相关,因此它对于测量亚急性腰痛治疗方式的有效性是有效的。