难治性抑郁症药物治疗管理的批判性综述。
A critical overview of the pharmacologic management of treatment-resistant depression.
作者信息
Nierenberg Andrew A, Katz Judith, Fava Maurizio
机构信息
Depression Clinical and Research Program, Massachusetts General Hospital, 50 Staniford Street, Boston, MA 02114, USA.
出版信息
Psychiatr Clin North Am. 2007 Mar;30(1):13-29. doi: 10.1016/j.psc.2007.01.001.
PMID:17362800
Abstract
Major depressive disorder is a frequent, serious disorder that usually responds partially to treatment and leaves many patients with treatment resistance. This article reviews and critically evaluates the evidence for the management of treatment-resistant depression and examines pharmacologic approaches to alleviate the suffering of patients who benefit insufficiently from initial treatment.
摘要
重度抑郁症是一种常见且严重的疾病，通常对治疗仅部分有效，导致许多患者出现治疗抵抗。本文回顾并批判性地评估了难治性抑郁症管理的证据，并探讨了药物治疗方法，以减轻那些从初始治疗中获益不足的患者的痛苦。
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