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盆底变形的有限元研究

Finite element studies of the deformation of the pelvic floor.

作者信息

Martins J A C, Pato M P M, Pires E B, Jorge R M Natal, Parente M, Mascarenhas T

机构信息

Department of Civil Engineering and Architecture and ICIST, Instituto Superior Técnico, Technical University of Lisbon, Lisbon, Portugal.

出版信息

Ann N Y Acad Sci. 2007 Apr;1101:316-34. doi: 10.1196/annals.1389.019. Epub 2007 Mar 15.

Abstract

This article describes research involving finite element simulations of women's pelvic floor, undertaken in the engineering schools of Lisbon and Oporto, in collaboration with the medical school of Oporto. These studies are motivated by the pelvic floor dysfunctions that lead namely to urinary incontinence and pelvic organ prolapse. This research ultimately aims at: (i) contributing to clarify the primary mechanism behind such disorders; (ii) providing tools to simulate the pelvic floor function and the effects of its dysfunctions; (iii) contributing to planning and performing surgeries in a more controlled and reliable way. The finite element meshes of the levator ani are based on a publicly available geometric data set, and use triangular thin shell or special brick elements. Muscle and soft tissues are assumed as (quasi-)incompressible hyperelastic materials. Skeletal muscles are transversely isotropic with a single fiber direction, embedded in an isotropic matrix. The fibers considered in this work may be purely passive, or active with input of neuronal excitation and consideration of the muscle activation process. The first assumption may be adequate to simulate passive deformations of the pelvic muscles and tissues (namely, under the extreme loading conditions of childbirth). The latter may be adequate to model faster contractions that occur in time intervals of the same order as those of muscle activation and deactivation (as in preventing urinary incontinence in coughing or sneezing). Numerical simulations are presented for the active deformation of the levator ani muscle under constant pressure and neural excitation, and for the deformation induced by a vaginal childbirth.

摘要

本文描述了在里斯本和波尔图的工程学院与波尔图医学院合作开展的关于女性盆底有限元模拟的研究。这些研究的动机是盆底功能障碍,尤其是导致尿失禁和盆腔器官脱垂的功能障碍。这项研究最终旨在:(i)有助于阐明此类疾病背后的主要机制;(ii)提供模拟盆底功能及其功能障碍影响的工具;(iii)有助于以更可控和可靠的方式规划和实施手术。肛提肌的有限元网格基于一个公开可用的几何数据集,并使用三角形薄壳或特殊砖块单元。肌肉和软组织被假定为(准)不可压缩的超弹性材料。骨骼肌在单一纤维方向上是横向各向同性的,嵌入在各向同性基质中。本研究中考虑的纤维可能是纯被动的,或者是在输入神经元兴奋并考虑肌肉激活过程的情况下是主动的。第一个假设可能足以模拟盆底肌肉和组织的被动变形(即在分娩的极端负荷条件下)。后者可能足以模拟在与肌肉激活和失活相同时间尺度的时间间隔内发生的更快收缩(如在咳嗽或打喷嚏时预防尿失禁)。文中给出了在恒定压力和神经兴奋下肛提肌主动变形以及阴道分娩引起的变形的数值模拟结果。

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