来自健康和患病犬类以及家养鸽子的中间葡萄球菌分离株中多重抗菌药物耐药性的高发生率。

High occurrence of multi-antimicrobial resistance in Staphylococcus intermedius isolates from healthy and diseased dogs and domesticated pigeons.

作者信息

Futagawa-Saito Keiko, Ba-Thein William, Fukuyasu Tsuguaki

机构信息

Department of Animal Health 2, School of Veterinary Medicine, Azabu University, 1-17-71 Fuchinobe, Sagamihara, Kanagawa 229-8501, Japan.

出版信息

Res Vet Sci. 2007 Dec;83(3):336-9. doi: 10.1016/j.rvsc.2007.01.013. Epub 2007 Mar 26.

DOI:10.1016/j.rvsc.2007.01.013

PMID:17368493

Abstract

Staphylococcus intermedius isolates (n=106), including 44 dog isolates and 62 pigeon isolates, were examined for their susceptibility to ampicillin, cephalexin, erythromycin, gentamicin, kanamycin, lincomycin, norfloxacin, oxacillin, tetracycline, and vancomycin by standard disk-diffusion test. The frequencies of resistance to ampicillin, kanamycin, and tetracycline were significantly higher in dog isolates than pigeon isolates (95.5% vs. 0%, 31.8% vs. 0%, and 45.5% vs. 9.7%, respectively; P<0.01). Antimicrobial resistance patterns of dog isolates and pigeon isolates were categorized respectively into nine and five distinct profiles. Significantly higher occurrence of resistance to two or more antimicrobials was observed in dog isolates than pigeon isolates (54.5% vs. 12.9%; P<0.01) and also in domesticated pigeon isolates than non-domesticated pigeon isolates (53.3% vs. 0%; P<0.01).

摘要

通过标准纸片扩散试验，对106株中间葡萄球菌分离株（包括44株犬源分离株和62株鸽源分离株）进行了氨苄西林、头孢氨苄、红霉素、庆大霉素、卡那霉素、林可霉素、诺氟沙星、苯唑西林、四环素和万古霉素的药敏试验。犬源分离株对氨苄西林、卡那霉素和四环素的耐药频率显著高于鸽源分离株（分别为95.5%对0%、31.8%对0%和45.5%对9.7%；P<0.01）。犬源分离株和鸽源分离株的抗菌耐药模式分别分为9种和5种不同的类型。犬源分离株中对两种或更多抗菌药物耐药的发生率显著高于鸽源分离株（54.5%对12.9%；P<0.01），并且在驯化鸽源分离株中也显著高于未驯化鸽源分离株（53.3%对0%；P<0.01）。