不同浓度罗哌卡因硬膜外麻醉对七氟醚需求量的影响。
The effect of epidural anesthesia with different concentrations of ropivacaine on sevoflurane requirements.
作者信息
Zhang Jie, Zhang Wei, Li Bin
机构信息
Department of Anesthesiology, The First Affiliated Hospital of ZhengZhou University, No. 1 East-JianShe Road, ZhengZhou 450052, China.
出版信息
Anesth Analg. 2007 Apr;104(4):984-6. doi: 10.1213/01.ane.0000258765.16164.27.
BACKGROUND
We evaluated sevoflurane requirements during combined general-epidural anesthesia with different concentration of ropivacaine.
METHODS
Fifty-six patients were randomly divided into three groups to epidurally receive saline, 0.2% ropivacaine or 1% ropivacaine. Sevoflurane concentration was adjusted to maintain certain anesthesia depth. BIS values and end-tidal sevoflurane concentrations were recorded at time points of pre-intubation and 5 min, 10 min, 15 min, 20 min, 25 min, 30 min after intubation.
RESULTS
End-tidal sevoflurane was significantly lower in the group receiving higher concentration of sevoflurane.
CONCLUSIONS
Epidural anesthesia can decrease sevoflurane requirements to a larger extent when a higher concentration of ropivacaine was applied.
背景
我们评估了在不同浓度罗哌卡因的全麻联合硬膜外麻醉期间七氟醚的需求量。
方法
56例患者随机分为三组，硬膜外分别给予生理盐水、0.2%罗哌卡因或1%罗哌卡因。调整七氟醚浓度以维持一定的麻醉深度。在插管前以及插管后5分钟、10分钟、15分钟、20分钟、25分钟、30分钟记录脑电双频指数（BIS）值和呼气末七氟醚浓度。
结果
接受较高浓度罗哌卡因的组呼气末七氟醚浓度显著降低。
结论
当应用较高浓度罗哌卡因时，硬膜外麻醉可更大程度降低七氟醚需求量。
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