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Cox迷宫手术中缝合技术的优越性:与射频消融术的比较。

Superiority of cut-and-sew technique for the Cox maze procedure: comparison with radiofrequency ablation.

作者信息

Stulak John M, Dearani Joseph A, Sundt Thoralf M, Daly Richard C, McGregor Christopher G A, Zehr Kenton J, Schaff Hartzell V

机构信息

Division of Cardiovascular Surgery, Mayo Clinic and Foundation, Rochester, Minn 55905, USA.

出版信息

J Thorac Cardiovasc Surg. 2007 Apr;133(4):1022-7. doi: 10.1016/j.jtcvs.2006.09.115. Epub 2007 Feb 22.

Abstract

OBJECTIVE

Although radiofrequency ablation is increasingly used to create the atrial lesions of the Cox maze procedure, its effectiveness in ablating atrial fibrillation compared with the standard cut-and-sew method is not known. We compare the freedom from atrial fibrillation in patients undergoing both methods with identical lesion sets.

METHODS

Radiofrequency ablation was used to create full Cox maze lesions in 56 patients between January 2002 and February 2005; these patients were matched with those who underwent the standard cut-and-sew method. Matched variables were gender (33 male, 23 female, both), age (67.5 vs 67.2 years), New York Heart Association class (mean 2.28 vs 1.96), atrial fibrillation type (37 paroxysmal, 19 continuous, both), and concomitant mitral valve surgery (37 in both). Hypertension, preoperative left atrial size, and preoperative duration of atrial fibrillation were similar between groups.

RESULTS

When compared with matched controls, fewer patients undergoing radiofrequency ablation were free from atrial fibrillation at dismissal (63% vs 88%; P = .0039) and at last follow-up (62% vs 92%; P = .016). According to logistic regression for matched pairs, patients undergoing radiofrequency ablation were 4.5 times more likely to be in atrial fibrillation at dismissal (95% confidence intervals [CI], 1.8, 10.9) and 5 times more likely to be in atrial fibrillation at follow-up (95% CI, 1.4, 17.3). No other covariate was associated with atrial fibrillation status at hospital dismissal or follow-up.

CONCLUSION

Creating Cox maze lesions with radiofrequency ablation is associated with less freedom from atrial fibrillation both early and late postoperatively. Because transmurality can be assured, the standard cut-and-sew Cox maze procedure remains the gold standard for the surgical treatment of atrial fibrillation.

摘要

目的

尽管射频消融术越来越多地用于Cox迷宫手术中的心房造口,但与标准的切割缝合方法相比,其在消融心房颤动方面的有效性尚不清楚。我们比较了采用两种方法且造口相同的患者发生心房颤动的情况。

方法

2002年1月至2005年2月期间,对56例患者使用射频消融术制作完整的Cox迷宫造口;这些患者与接受标准切割缝合方法的患者进行匹配。匹配变量包括性别(男性33例,女性23例,两组相同)、年龄(67.5岁对67.2岁)、纽约心脏协会分级(平均2.28对1.96)、心房颤动类型(阵发性37例,持续性19例,两组相同)以及同期二尖瓣手术(两组均为37例)。两组间高血压、术前左心房大小和术前心房颤动持续时间相似。

结果

与匹配的对照组相比,接受射频消融术的患者在出院时无房颤的比例更低(63%对88%;P = 0.0039),在末次随访时也更低(62%对92%;P = 0.016)。根据配对逻辑回归分析,接受射频消融术的患者在出院时发生房颤的可能性高出4.5倍(95%置信区间[CI],1.8,10.9),在随访时发生房颤的可能性高出5倍(95%CI,1.4,17.3)。在出院或随访时,没有其他协变量与房颤状态相关。

结论

使用射频消融术制作Cox迷宫造口与术后早期和晚期房颤发生率较低有关。由于可以确保透壁性,标准的切割缝合Cox迷宫手术仍然是心房颤动外科治疗的金标准。

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