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糖尿病与性功能障碍:来自奥姆斯特德县男性泌尿系统症状与健康状况研究的结果

Diabetes and sexual dysfunction: results from the Olmsted County study of urinary symptoms and health status among men.

作者信息

Burke James P, Jacobson Debra J, McGree Michaela E, Nehra Ajay, Roberts Rosebud O, Girman Cynthia J, Lieber Michael M, Jacobsen Steven J

机构信息

Division of Epidemiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

出版信息

J Urol. 2007 Apr;177(4):1438-42. doi: 10.1016/j.juro.2006.11.059.

Abstract

PURPOSE

We examined the association of diabetes and domains of sexual dysfunction in a population based sample of men residing in Olmsted County, Minnesota.

MATERIALS AND METHODS

A cohort of 2,115 white men 40 to 79 years old as of January 1, 1990 was randomly selected from the Olmsted County population. Men who had a history of prostate or bladder surgery, urethral surgery or stricture, or medical or other neurological condition that could affect normal urinary function were excluded from analysis. Diabetes itself was not used as an exclusionary criterion, although those with end stage organ failure as a result of diabetes were excluded. A previously validated male sexual function index was included in the questionnaires administrated to the cohort in 1996, which consisted of 11 questions on the 5 sexual function domains of sexual drive, erectile function, ejaculatory function, sexual problem assessment and sexual satisfaction. The baseline questionnaire also included whether they had ever been diagnosed by a physician as having diabetes. Only men with regular sexual partners were included.

RESULTS

Individuals with diabetes at baseline had significantly greater dysfunction in all 5 sexual function domains. In multivariate adjusted analyses diabetes was significantly associated with all sexual dysfunction domains. The associations remained significant after adjusting for numerous predictors of sexual dysfunction.

CONCLUSIONS

The presence of diabetes at baseline was significantly associated not only with erectile dysfunction but with all aspects of sexual dysfunction, including sexual drive, ejaculatory function, sexual problems and sexual satisfaction in this population based sample of men residing in Olmsted County.

摘要

目的

我们在明尼苏达州奥尔姆斯特德县的男性人群样本中,研究了糖尿病与性功能障碍各领域之间的关联。

材料与方法

从奥尔姆斯特德县人口中随机抽取了一组2115名40至79岁的白人男性,这些男性截至1990年1月1日。有前列腺或膀胱手术史、尿道手术或狭窄史,或患有可能影响正常排尿功能的医学或其他神经系统疾病的男性被排除在分析之外。糖尿病本身不作为排除标准,尽管因糖尿病导致终末期器官衰竭的患者被排除。1996年对该队列进行问卷调查时,纳入了一个先前经过验证的男性性功能指数,该指数由11个关于性欲、勃起功能、射精功能、性问题评估和性满意度这5个性功能领域的问题组成。基线调查问卷还包括他们是否曾被医生诊断患有糖尿病。仅纳入有固定性伴侣的男性。

结果

基线时患有糖尿病的个体在所有5个性功能领域的功能障碍明显更严重。在多变量调整分析中,糖尿病与所有性功能障碍领域均显著相关。在对众多性功能障碍预测因素进行调整后,这种关联仍然显著。

结论

在这个以奥尔姆斯特德县男性为样本的人群中,基线时糖尿病的存在不仅与勃起功能障碍显著相关,而且与性功能障碍的各个方面相关,包括性欲、射精功能、性问题和性满意度。

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